公开(公告)号：EP2293718B1

公开(公告)日：2017-07-26

申请号：EP09743762.8

申请日：2009-05-08

申请人： Edwards Lifesciences Corporation

发明人： CARPENTIER, Alain, F. ,  ADAMS, David, H. ,  ADZICH, Vaso

IPC分类号： A61B5/103 ,  A61F2/24

CPC分类号： A61F2/2448 ,  A61F2250/0018 ,  A61F2250/0029

公开(公告)号：EP2068769A2

公开(公告)日：2009-06-17

申请号：EP07871043.1

申请日：2007-08-23

申请人： Edwards Lifesciences Corporation

发明人： ADZICH, Vaso ,  INGLE, Aaron ,  WINSTON, Matthew

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61B2017/00243 ,  A61F2/2448 ,  A61F2/2466

摘要： An annuloplasly ring and ring holder combination includes a generally triangular-shaped ring and a generally T-shaped holder. The ring holder has a base portion forming the top of the T shape and engaging against a first segment of the ring, with a radial arm extending from the base portion and forming the post of the T. The radial arm engages against a junction between two segments of the ring. The invention includes placements of suture holes and cutting wells which, in combination with the improved ring holder shape, afford the user improved access and visibility to the surgical site, the ring, and to the suture that is used to retain the annuloplasty ring to the holder.

公开(公告)号：EP2185107B1

公开(公告)日：2017-01-25

申请号：EP08829653.8

申请日：2008-09-08

申请人： Edwards Lifesciences Corporation

发明人： KEIDAR, Yaron ,  ADZICH, Vaso ,  ROTTENBERG, Dan ,  MANASH, Boaz ,  NAHSHON, Alon

IPC分类号： A61F2/24

CPC分类号： A61F2/2466 ,  A61F2/2427 ,  A61F2/2448

摘要： An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle.

公开(公告)号：EP1861044B1

公开(公告)日：2012-07-11

申请号：EP06748596.1

申请日：2006-03-23

申请人： Edwards Lifesciences Corporation

发明人： ADZICH, Vaso ,  INGLE, Aaron ,  FANN, Hilda

IPC分类号： A61F2/24

CPC分类号： A61F2/2448 ,  A61B2017/00243 ,  A61F2/2466

摘要： An annuloplasty ring holder includes an angled post for improved visibility and access by the surgeon. The post may be configured to be adjusted in angle and rotation. The ring holder can include a relatively open lower template, including relatively narrow extending radial arms with short, generally arcuate ring-retaining distal portions. The invention includes placements of suture holes and cutting wells which, in combination with improved suture routing, afford the user improved access to cutting the suture that is used to retain the annuloplasty ring to the holder.

摘要翻译： 瓣环成形术环托架包括成角度的柱以改善外科医生的可视性和进入。 该帖子可以配置为可以调整角度和旋转角度。 环支架可以包括相对开放的下模板，其包括具有短的，大致弧形的环保持远端部分的相对窄的延伸径向臂。 本发明包括缝合孔和切割井的放置，其与改进的缝合线路径相结合为使用者提供了改进的切入缝合线的通路，该缝合线用于将瓣环成形术环保持到保持器。

公开(公告)号：EP1861044A2

公开(公告)日：2007-12-05

申请号：EP06748596.1

申请日：2006-03-23

申请人： Edwards Lifesciences Corporation

发明人： ADZICH, Vaso ,  INGLE, Aaron ,  FANN, Hilda

IPC分类号： A61F2/24

CPC分类号： A61F2/2448 ,  A61B2017/00243 ,  A61F2/2466

摘要： An annuloplasty ring holder includes an angled post for improved visibility and access by the surgeon. The post may be configured to be adjusted in angle and rotation. The ring holder can include a relatively open lower template, including relatively narrow extending radial arms with short, generally arcuate ring-retaining distal portions. The invention includes placements of suture holes and cutting wells which, in combination with improved suture routing, afford the user improved access to cutting the suture that is used to retain the annuloplasty ring to the holder.

摘要翻译： 瓣环成形术环托架包括成角度的柱以改善外科医生的可视性和进入。 该帖子可以配置为可以调整角度和旋转角度。 环支架可以包括相对开放的下模板，其包括具有短的，大致弧形的环保持远端部分的相对窄的延伸径向臂。 本发明包括缝合孔和切割井的放置，其与改进的缝合线路径相结合为使用者提供了改进的切入缝合线的通路，该缝合线用于将瓣环成形术环保持到保持器。

公开(公告)号：EP2068770B1

公开(公告)日：2011-02-23

申请号：EP07871051.4

申请日：2007-08-29

申请人： Edwards Lifesciences Corporation

发明人： INGLE, Aaron ,  ADZICH, Vaso

IPC分类号： A61F2/24

CPC分类号： A61F2/2448 ,  A61F2002/30199 ,  A61F2230/0063

摘要： A mitral annuloplasty ring that has a saddle shape with an upward bow in both an anterior segment and a posterior portion, with the upward bow being more pronounced in the anterior segment. The ring defines a closed ring body with a rounded isosceles triangular shape and the anterior segment along a long side. The posterior portion bulges outward to create a minor-major axis dimension ratio of between about 3.3:4 to 4:4. An inner ring body is made of a generally rigid material such as titanium that will substantially resist distortion when subjected to the stress imparted thereon after implantation in the mitral valve annulus of an operating human heart. The outward and upward posterior bow of the annuloplasty ring corrects for pathologies associated with mitral valve prolapse, as seen with Barlow's syndrome for instance, in which the leaflets tend to be elongated or floppy. The anterior segment has an enhanced upward bow to conform to systolic mitral annulus shapes, and the upward posterior bow is somewhat lower, for example between 1-2 mm lower, to help reduce the chance of suture pull-out, or dehiscence.

公开(公告)号：EP1903990A1

公开(公告)日：2008-04-02

申请号：EP06785615.3

申请日：2006-06-27

申请人： Edwards Lifesciences Corporation

发明人： PERIER, Patrick ,  ADZICH, Vaso

IPC分类号： A61F2/24

CPC分类号： A61B17/02 ,  A61B17/0469 ,  A61B2017/00243 ,  A61B2017/06057 ,  A61F2/2457 ,  A61F2/2466

摘要： The invention is an apparatus, system, and method for repairing heart valves. A suture line is secured to a papillary muscle, and then passed through a portion of a heart valve leaflet. A reference element (106) is provided at a desired distance from a plane defined by the heart valve annulus (100) . The suture line is secured to the heart valve leaflet at a position adjacent the reference element. The reference element may part of a device configured for placement on or in a heart valve annulus . The reference element may be slidingly secured to the device so that the distance of the reference element from the main body of the device can be varied by a surgeon or other user. The reference element may be a line of suture, which may be pre-installed during manufacture of the device or may be installed by the surgeon or other user.

公开(公告)号：EP2068769B1

公开(公告)日：2015-07-08

申请号：EP07871043.1

申请日：2007-08-23

申请人： Edwards Lifesciences Corporation

发明人： ADZICH, Vaso ,  INGLE, Aaron ,  WINSTON, Matthew

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61B2017/00243 ,  A61F2/2448 ,  A61F2/2466

公开(公告)号：EP1903990B1

公开(公告)日：2015-02-25

申请号：EP06785615.3

申请日：2006-06-27

申请人： Edwards Lifesciences Corporation

发明人： PERIER, Patrick ,  ADZICH, Vaso

IPC分类号： A61F2/24

CPC分类号： A61B17/02 ,  A61B17/0469 ,  A61B2017/00243 ,  A61B2017/06057 ,  A61F2/2457 ,  A61F2/2466

公开(公告)号：EP2293718A1

公开(公告)日：2011-03-16

申请号：EP09743762.8

申请日：2009-05-08

申请人： Edwards Lifesciences Corporation

发明人： CARPENTIER, Alain, F. ,  ADAMS, David, H. ,  ADZICH, Vaso

IPC分类号： A61B5/103 ,  A61F2/24

CPC分类号： A61F2/2448 ,  A61F2250/0018 ,  A61F2250/0029

摘要： Annuloplasty rings optimally sized to take into account more of the common degenerative valve pathologies. Each ring has a structural ring body with a shape that complies with predicted shapes of degenerative valvular diseases, such as Fibroelastic deficiency (FED), Marfan's or Barlow's. The predicted shapes are obtained through careful echocardiographic and intraoperative measurements, and often differ for different annulus orifice sizes. For instance, in mitral rings the larger rings have larger minor axis and oblique axis dimensions relative to their major axis dimensions, and are more circular as opposed to D-shaped. The rings may also be three-dimensional and the relative heights around the rings may change for different sized rings. A mitral ring may have a higher anterior saddle relative to a posterior saddle, with the relative heights varying across the ring sizes. The ring may have varying flexibility around the ring periphery which also changes for different ring sizes. A bulge on the sewing cuff forms a step on the outflow side for ease of suturing, which may be indicated by a suture line.

摘要翻译： 瓣膜成形术环最优化以考虑更多的常见的退行性瓣膜病变。 每个戒指都有一个结构环体，其形状符合退化性瓣膜疾病的预测形状，如纤维弹力不足（FED），马凡或巴洛氏。 通过仔细的超声心动图和术中测量获得预测的形状，并且对于不同的环形孔尺寸通常是不同的。 例如，在二尖瓣环中，较大的环相对于其长轴尺寸具有较大的短轴和斜轴尺寸，并且与D形相反更圆。 环也可以是三维的，并且围绕环的相对高度可以针对不同尺寸的环而改变。 二尖瓣可能具有相对于后鞍座的较高的前鞍座，相对高度在环尺寸之间变化。 环可以围绕环周边具有不同的柔性，这也适用于不同的环尺寸。 缝合套管上的凸起在流出侧形成一个便于缝合的步骤，这可以由缝合线表示。