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公开(公告)号：EP4257086A2
公开(公告)日：2023-10-11
申请号：EP23194469.5
申请日：2016-11-09
发明人： Gurovich, Nikolay , Jafari, Mohammad , Tayeb, Liron , Tamir, Ilan , Yohanan, Ziv , Nir, Noam , Maimon, David , Manash, Boaz
IPC分类号： A61F2/24
摘要： Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A prosthetic valve may comprise a radially compressible main body and a one-way valve portion. The prosthetic valve may further comprise one or more ventricular anchors coupled to the main body and disposed outside of the main body. The ventricular anchors may be configured such that a reduced profile of the prosthetic valve is possible. A space may be provided between an outer surface of the main body and the ventricular anchors for receiving native mitral valve leaflets. The prosthetic valve may include an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for receiving the native mitral valve leaflets between the ventricular anchors and the main body are described.
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公开(公告)号：EP4085872A1
公开(公告)日：2022-11-09
申请号：EP22174253.9
申请日：2018-01-23
发明人： Haivatov, Sara , Perlmutter, Khen , Patel, Darshin S. , Manash, Boaz , Chadha, Ajay , Chu, Waina Michelle , Chhe, Chambory , Schwartz, Evan T. , Pawar, Sandip Vasant
摘要： A prosthetic heart valve includes a frame having a plurality of strut members, an inflow end, and an outflow end. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering has a first layer and a second layer, wherein the second layer has a plush surface. The first layer is folded over a circumferential edge portion of the second layer to form a protective portion that extends beyond the strut members in a direction along a longitudinal axis of the prosthetic heart valve.
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公开(公告)号：EP4151180A1
公开(公告)日：2023-03-22
申请号：EP22190449.3
申请日：2017-08-25
IPC分类号： A61F2/24
摘要： Docking devices can be configured to be positioned at a native valve of a human heart to provide structural support for docking a prosthetic valve. The docking devices generally have coiled structures that define an inner space in which the prosthetic valve can be held. Some docking devices can be adjusted from a first wider configuration which facilitates easier advancement of the docking device around the valve anatomy, to a second narrower configuration after the docking device has been delivered to more securely hold the prosthetic valve. The docking device may also be better held in position at the native valve after adjustment to the narrower configuration. Some docking devices include a stabilization segment or double coil configuration, where a main coil region is configured to securely hold a prosthetic valve, while a stabilization coil region is configured to more stably hold the docking device at the native valve.
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公开(公告)号：EP4445879A2
公开(公告)日：2024-10-16
申请号：EP24196348.7
申请日：2019-10-18
发明人： Dvorsky, Anatoly , Levi, Tamir S. , Neumann, Yair A. , Axelrod, Noa , Atias, Eitan , Cohen, Oren , Schwarcz, Elazar Levi , Witzman, Ofir , Miller, Noam , Manash, Boaz , Garmahi, Danny M.
IPC分类号： A61F2/95
摘要： An implantable prosthetic device can include a frame that is radially expandable and compressible between a radially compressed configuration and a radially expanded configuration. The frame can have a first set of a plurality of struts extending in a first direction, and a second set of a plurality of struts extending in a second direction, and each strut of the first set of struts can be pivotably connected to at least one strut of the second set of struts. Each strut can be curved helically with respect to a first, longitudinal axis of the frame, and each strut can be curved with respect to a second axis that is perpendicular to the first, longitudinal axis of the frame.
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公开(公告)号：EP4410238A2
公开(公告)日：2024-08-07
申请号：EP24162906.2
申请日：2019-01-18
发明人： Schwartz, Evan T. , Chow, Sean , Pawar, Sandip Vasant , Patel, Darshin S. , Chhe, Chambory , Laddha, Arpit , Nguyen, Ngoc Hoang Thi , Chu, Waina Michelle , Du, Yuanlong , Bukin, Michael , Manash, Boaz , Haivatov, Sara , Levi, Tamir S.
IPC分类号： A61F2/00
CPC分类号： A61F2/0077 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2250/006920130101 , A61F2230/005420130101 , A61F2230/009120130101 , A61F2210/007620130101 , A61F2220/007520130101
摘要： A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.
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公开(公告)号：EP4257086A3
公开(公告)日：2023-12-20
申请号：EP23194469.5
申请日：2016-11-09
发明人： Gurovich, Nikolay , Jafari, Mohammad , Tayeb, Liron , Tamir, Ilan , Yohanan, Ziv , Nir, Noam , Maimon, David , Manash, Boaz
IPC分类号： A61F2/24
摘要： Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A prosthetic valve may comprise a radially compressible main body and a one-way valve portion. The prosthetic valve may further comprise one or more ventricular anchors coupled to the main body and disposed outside of the main body. The ventricular anchors may be configured such that a reduced profile of the prosthetic valve is possible. A space may be provided between an outer surface of the main body and the ventricular anchors for receiving native mitral valve leaflets. The prosthetic valve may include an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for receiving the native mitral valve leaflets between the ventricular anchors and the main body are described.
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公开(公告)号：EP4410238A3
公开(公告)日：2024-11-06
申请号：EP24162906.2
申请日：2019-01-18
发明人： Schwartz, Evan T. , Chow, Sean , Pawar, Sandip Vasant , Patel, Darshin S. , Chhe, Chambory , Laddha, Arpit , Nguyen, Ngoc Hoang Thi , Chu, Waina Michelle , Du, Yuanlong , Bukin, Michael , Manash, Boaz , Haivatov, Sara , Levi, Tamir S.
摘要： A prosthetic heart valve includes a frame having an inflow end and an outflow end, and defining a longitudinal axis. The prosthetic heart valve further includes a leaflet structure situated at least partially within the frame, and a covering disposed around the frame. The covering includes a first woven portion extending circumferentially around the frame and including a plurality of texturized strands or yarns extending along the longitudinal axis of the frame. The covering further includes a second woven portion extending circumferentially around the frame and spaced apart from the first woven portion along the longitudinal axis of the frame. The texturized strands extend along the longitudinal axis of the frame from the first woven portion to the second woven portion and form a floating portion between the first woven portion and the second woven portion.
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公开(公告)号：EP4438008A2
公开(公告)日：2024-10-02
申请号：EP24174470.5
申请日：2016-11-08
发明人： Tamir, Ilan , Nir, Noam , Manash, Boaz , Maimon, David , Cohen, Oren
IPC分类号： A61F2/24
CPC分类号： A61F2/2439 , A61F2/2436
摘要： Disclosed herein are embodiments of delivery capsules for delivering prosthetic implants around the relatively tight bends of a catheter. In particular, disclosed herein are delivery capsules including a tubular layer for holding the heart valve, a frame enclosing the tubular layer and an elongate element coupled to the frame for allowing the tubular layer and frame to expand. For example, the frame may be biased to expand and withdrawal of the elongate element from openings in the frame can release the frame to expand into a larger diameter. Another embodiment includes a helical wire wrapped around the capsule for easy delivery through bends and a second helical wire that is advanced between windings of the first helical wire to selectively stiffen the capsule for withdrawal. Other embodiments include sock-like capsules that can be crumpled into shorter lengths by pulling a pull line attached to the capsule.
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公开(公告)号：EP4299037A3
公开(公告)日：2024-04-10
申请号：EP23209714.7
申请日：2020-06-30
发明人： Levi, Tamir S. , Bukin, Michael , Nir, Noam , Yohanan, Ziv , Schwarcz, Elazar Levi , Cohen, Oren , Witzman, Ofir , Atias, Eitan , Miller, Noam , Perlmutter, Khen , Manash, Boaz , Leiba, Eyal , Goldberg, Eran
IPC分类号： A61F2/24
摘要： Various mechanically expandable prosthetic heart valves, as well as deliver apparatus, delivery assemblies, and methods for implanting such prosthetic heart valves. In one example, a prosthetic heart valve includes a mechanically expandable frame, a valve structure, and an actuator. The frame includes a plurality of struts and is movable between a radially compressed state and a radially expanded state. The valve structure includes a plurality of leaflets. The actuator is coupled to the frame and comprises an actuation lumen, a locking member, and a locking element. The actuation lumen is circumferentially spaced and axially parallel to the locking member. The actuation lumen is configured for receiving an axially movable actuation shaft that can move the frame between the radially compressed state and the radially expanded state. The locking element is rotatably coupled to the locking member and is configured to lock the frame at a desired state.
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公开(公告)号：EP4299037A2
公开(公告)日：2024-01-03
申请号：EP23209714.7
申请日：2020-06-30
发明人： Levi, Tamir S. , Bukin, Michael , Nir, Noam , Yohanan, Ziv , Schwarcz, Elazar Levi , Cohen, Oren , Witzman, Ofir , Atias, Eitan , Miller, Noam , Perlmutter, Khen , Manash, Boaz , Leiba, Eyal , Goldberg, Eran
IPC分类号： A61F2/24
摘要： Various mechanically expandable prosthetic heart valves, as well as deliver apparatus, delivery assemblies, and methods for implanting such prosthetic heart valves. In one example, a prosthetic heart valve includes a mechanically expandable frame, a valve structure, and an actuator. The frame includes a plurality of struts and is movable between a radially compressed state and a radially expanded state. The valve structure includes a plurality of leaflets. The actuator is coupled to the frame and comprises an actuation lumen, a locking member, and a locking element. The actuation lumen is circumferentially spaced and axially parallel to the locking member. The actuation lumen is configured for receiving an axially movable actuation shaft that can move the frame between the radially compressed state and the radially expanded state. The locking element is rotatably coupled to the locking member and is configured to lock the frame at a desired state.
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