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公开(公告)号：EP3187491A1
公开(公告)日：2017-07-05
申请号：EP15836577.5
申请日：2015-08-26
发明人： NAKAMURA, Taiju , ABE, Taichi , MIYASHITA, Yusuke , KURODA, Hirofumi , AYATA, Yusuke , AKAO, Atsushi
IPC分类号： C07D215/48 , A61K31/47 , A61P35/00
CPC分类号： C07D215/48 , A61K31/47
摘要： Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
摘要翻译： 提供由式（IV）表示的化合物或其盐，其中由式（I）表示的化合物的含量为350质量ppm以下。
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公开(公告)号：EP4361143A1
公开(公告)日：2024-05-01
申请号：EP22864456.3
申请日：2022-08-29
发明人： NAGAI, Mitsuo , FUKUYAMA, Takashi , KAMADA, Yasuaki , NIIJIMA, Jun , KURODA, Hirofumi , MURAKAMI, Keiichi , KAROJI, Yuki , SAITO, Hiroyuki , OMORI, Masayuki , MIYASHITA, Yusuke , KAMADA, Atsushi , MATSUDA, Masaaki , KODERA, Takanori
IPC分类号： C07D401/14
CPC分类号： Y02P20/55 , C07D401/14
摘要： Provided is compound (3d) or a salt thereof, wherein the content of compound (IM-7) is 0.48 mass% or lower.
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公开(公告)号：EP4361139A1
公开(公告)日：2024-05-01
申请号：EP22864455.5
申请日：2022-08-29
发明人： NAGAI, Mitsuo , FUKUYAMA, Takashi , KAMADA, Yasuaki , NIIJIMA, Jun , KURODA, Hirofumi , KAROJI, Yuki , MURAKAMI, Keiichi , OMORI, Masayuki , MIYASHITA, Yusuke , KAMADA, Atsushi , MATSUDA, Masaaki
IPC分类号： C07D401/12 , C07D209/32
CPC分类号： Y02P20/55 , C07D401/12 , C07D209/32
摘要： The invention provides a production process allowing more high-yield and efficient synthesis of key intermediates (compound (2i) or a salt thereof, and compound (1g)) for production of E7090, which is useful as an FGFR inhibitor.
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