公开(公告)号：EP2962724A1

公开(公告)日：2016-01-06

申请号：EP15176003.0

申请日：2011-08-31

申请人： Electrocore LLC

发明人： Errico, Joseph P. ,  Simon, Bruce ,  Raffle, John T.

IPC分类号： A61N1/00 ,  A61N1/04 ,  A61N1/36

CPC分类号： A61N1/36021 ,  A61M21/00 ,  A61M2021/0022 ,  A61M2021/0027 ,  A61M2021/0044 ,  A61M2021/0072 ,  A61N1/0456 ,  A61N1/0496 ,  A61N1/36014 ,  A61N1/36025 ,  A61N1/36053 ,  A61N1/40

摘要： The invention relates to a device for modulating one or more nerves within a body of a patient comprising:
- a handheld device (300) comprising a enclosure with an interior and an interface configured for contact with an outer skin surface of a patient;
- a source of energy (320) housed within the interior of the enclosure, wherein the source of energy is configured to generate an electrical field comprising bursts of pulses with a frequency of about 5 to about 100 bursts per second;
- one or more electrodes (340, 45) housed within the enclosure;
- a conduction medium (350) within the enclosure and electrically coupling the electrodes with the interface; and
wherein the source of energy is configured to apply an electrical impulse through the interface of the enclosure transcutaneously through an outer skin surface of the patient to a nerve at a target region below the outer skin surface,
wherein the electrical impulse is sufficient to modulate a nerve within the target region and insufficient to substantially modulate nerve(s) in the vicinity of the outer skin surface.

摘要翻译： 本发明涉及一种用于调节患者体内的一个或多个神经的装置，包括： - 手持装置（300），包括具有内部的外壳和被配置为与患者的外表皮肤接触的接口; - 容纳在所述外壳内部的能量源（320），其中所述能量源被配置为产生电场，所述电场包括频率为每秒约5至约100个脉冲串的脉冲串; - 容纳在所述外壳内的一个或多个电极（340,45） - 外壳内的导电介质（350），并将电极与界面电耦合; 并且其中所述能量源被配置为经由所述外壳的界面经皮穿过所述患者的外表皮以将电脉冲施加到所述外皮肤表面下方的靶区域处的神经，其中所述电脉冲足以调制 目标区域内的神经，并且不足以基本上调节外皮表面附近的神经。

公开(公告)号：EP2962725A1

公开(公告)日：2016-01-06

申请号：EP15176007.1

申请日：2011-08-31

申请人： Electrocore LLC

发明人： Errico, Joseph P. ,  Simon, Bruce ,  Raffle, John T.

IPC分类号： A61N1/00 ,  A61N1/04 ,  A61N1/36

CPC分类号： A61N1/36021 ,  A61M21/00 ,  A61M2021/0022 ,  A61M2021/0027 ,  A61M2021/0044 ,  A61M2021/0072 ,  A61N1/0456 ,  A61N1/0496 ,  A61N1/36014 ,  A61N1/36025 ,  A61N1/36053 ,  A61N1/40

摘要： The invention relates to an apparatus (30, 50) for modulating one or more nerves within a body of a patient comprising:
- a source of energy (320) for generating an electric field;
- one or more electrodes (45, 345) coupled to the source of energy;
- an interface (351, 42) coupled to the electrodes and positionable against an outer skin surface of the patient;
- a conduction medium (350) electrically coupling the electrodes with the interface,
- a housing having an outer enclosure enclosing the electrodes and the conduction medium, wherein at least a portion of the outer enclosure comprises the interface;

and wherein the source of energy is configured to deliver one or more electrical impulses from the electrodes through the conductive medium, the interface and the outer skin surface to a nerve at a target region within the patient.

摘要翻译： 本发明涉及一种用于调节患者体内的一个或多个神经的装置（30,50），包括： - 用于产生电场的能量源（320）; - 耦合到能量源的一个或多个电极（45,345）; - 耦合到所述电极并且可抵靠所述患者的外表皮表面定位的界面（351,42）; - 导电介质（350），其将所述电极与所述界面电耦合; - 外壳，其具有封闭所述电极和所述传导介质的外壳，其中所述外壳的至少一部分包括所述界面; 并且其中所述能量源被配置成将来自所述电极的一个或多个电脉冲通过所述导电介质，所述界面和所述外皮表面递送到所述患者内的目标区域处的神经。