专利检索 ap:("Eli Lilly AND Company") AND inv:"Rubio, Almudena" 第 1 页

1.

发明公开
SELECTIVE ESTROGEN RECEPTOR DEGRADERS 审中-公开

公开(公告)号：EP4155310A1

公开(公告)日：2023-03-29

申请号：EP22201995.2

申请日：2019-07-11

申请人： Eli Lilly and Company

发明人： Bastian, Jolie Anne , Cohen, Jeffrey Daniel , McMahon, Jennifer Anne , Rubio, Almudena , Sall, Daniel John

IPC分类号： C07D491/052 , A61K31/436 , A61P35/00

摘要： Novel selective estrogen receptor degraders (SERDs) according to the formula:

pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein either R 1 or R 2 is independently selected from Cl, F, -CF 3 , or -CH 3 , and the other is hydrogen, and methods for their use are provided.