公开(公告)号：EP3943076A2

公开(公告)日：2022-01-26

申请号：EP21181417.3

申请日：2015-12-17

申请人： Empros Pharma AB

发明人： ALDERBORN, Göran ,  FORSLUND, Anders ,  HOLMBÄCK, Ulf ,  LENNERNÄS, Hans ,  GRUDÉN, Jan, Stefan Persson

IPC分类号： A61K9/50 ,  A61K9/20 ,  A61K9/24 ,  A61K9/28 ,  A61K9/48 ,  A61K9/14 ,  A61K9/70 ,  A61K31/365 ,  A61K31/7008 ,  A61K31/702

摘要： The present invention relates to a modified-release oral composition comprising orlistat or acarbose, wherein the composition comprises two individually distinct parts with different release patterns, the composition comprises:
a part, G2B, comprising orlistat, an enteric polymer and a surfactant, and a part, G3, comprising orlistat and one or more of a surfactant, a water-soluble polymer, and a water-swellable polymer, or a part, G1, comprising acarbose and one or more of: a hydrophobic polymer, a lipid and a wax, and a part, G2A, comprising acarbose, an enteric polymer and a surfactant.

公开(公告)号：EP3943076A3

公开(公告)日：2022-04-13

申请号：EP21181417.3

申请日：2015-12-17

申请人： Empros Pharma AB

发明人： ALDERBORN, Göran ,  FORSLUND, Anders ,  HOLMBÄCK, Ulf ,  LENNERNÄS, Hans ,  GRUDÉN, Jan, Stefan Persson

IPC分类号： A61K9/50 ,  A61K9/20 ,  A61K9/24 ,  A61K9/28 ,  A61K9/48 ,  A61K9/14 ,  A61K9/70 ,  A61K31/365 ,  A61K31/7008 ,  A61K31/702

摘要： The present invention relates to a modified-release oral composition comprising orlistat or acarbose, wherein the composition comprises two individually distinct parts with different release patterns, the composition comprises:
a part, G2B, comprising orlistat, an enteric polymer and a surfactant, and a part, G3, comprising orlistat and one or more of a surfactant, a water-soluble polymer, and a water-swellable polymer, or a part, G1, comprising acarbose and one or more of: a hydrophobic polymer, a lipid and a wax, and a part, G2A, comprising acarbose, an enteric polymer and a surfactant.