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公开(公告)号：EP2468286A1
公开(公告)日：2012-06-27
申请号：EP12160849.1
申请日：2009-09-10
发明人： Ku, Yiyin , Or, Yat, Sun , Wagaw, Sable, H. , Engstrom, Ken , Grieme, Tim , Sheikh, Ahmad , Mei, Jianzhang , McDaniel, Keith, F. , Chen, Hui-ju , Shanley, Jason, P. , Kempf, Dale, J. , Grampovnik, David, J. , Sun, Ying , Liu, Dong , Gai, Yonghua
IPC分类号： A61K38/00 , A61K38/12 , C07D487/04
CPC分类号： C07K1/113 , C07D487/04
摘要： The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
摘要翻译： 本发明涉及新的大环化合物及其使用方法。 本发明还涉及包含本发明化合物或其药学上可接受的盐，酯或前药与药学上可接受的载体或赋形剂组合的药物组合物。
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公开(公告)号：EP2468285A1
公开(公告)日：2012-06-27
申请号：EP12160779.0
申请日：2009-09-10
发明人： Ku, Yiyin , Or, Yat, Sun , Wagaw, Sable, H. , Engstrom, Ken , Grieme, Tim , Sheikh, Ahmad , Mei, Jianzhang , McDaniel, Keith, F. , Chen, Hui-ju , Shanley, Jason, P. , Kempf, Dale, J. , Grampovnik, David, J. , Sun, Ying , Liu, Dong , Gai, Yonghua
IPC分类号： A61K38/00 , A61K38/12 , C07D487/04
CPC分类号： C07K1/113 , C07D487/04
摘要： The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
摘要翻译： 本发明涉及新的大环化合物及其使用方法。 本发明还涉及包含本发明化合物或其药学上可接受的盐，酯或前药与药学上可接受的载体或赋形剂组合的药物组合物。
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公开(公告)号：EP2468287A1
公开(公告)日：2012-06-27
申请号：EP12161047.1
申请日：2009-09-10
发明人： Ku, Yiyin , Or, Yat, Sun , Wagaw, Sable, H. , Engstrom, Ken , Grieme, Tim , Sheikh, Ahmad , Mei, Jianzhang , McDaniel, Keith, F. , Chen, Hui-ju , Shanley, Jason, P. , Kempf, Dale, J. , Grampovnik, David, J. , Sun, Ying , Liu, Dong , Gai, Yonghua
IPC分类号： A61K38/00 , A61K38/12 , C07D487/04
CPC分类号： C07K1/113 , C07D487/04
摘要： The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
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4.发明授权
公开(公告)号：EP2468285B1
公开(公告)日：2014-10-15
申请号：EP12160779.0
申请日：2009-09-10
发明人： Ku, Yiyin , Or, Yat, Sun , Wagaw, Sable, H. , Engstrom, Ken , Grieme, Tim , Sheikh, Ahmad , Mei, Jianzhang , McDaniel, Keith, F. , Chen, Hui-ju , Shanley, Jason, P. , Kempf, Dale, J. , Grampovnik, David, J. , Sun, Ying , Liu, Dong , Gai, Yonghua
IPC分类号： A61K38/00 , A61K38/12 , C07D487/04
CPC分类号： C07K1/113 , C07D487/04
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公开(公告)号：EP2805726A1
公开(公告)日：2014-11-26
申请号：EP14181565.4
申请日：2009-09-10
发明人： Ku, Yiyin , Or, Yat, Sun , Wagaw, Sable, H. , Engstrom, Ken , Grieme, Tim , Sheikh, Ahmad , Mei, Jianzhang , McDaniel, Keith, F. , Chen, Hui-ju , Shanley, Jason, P. , Kempf, Dale, J. , Grampovnik, David, J. , Gai, Yonghua , Sun, Ying , Liu, Dong
IPC分类号： A61K38/00 , A61K38/12 , C07D487/04
CPC分类号： C07K1/113 , C07D487/04
摘要： The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
摘要翻译： 本发明涉及新的大环化合物及其使用方法。 本发明还涉及包含本发明化合物或其药学上可接受的盐，酯或前药与药学上可接受的载体或赋形剂组合的药物组合物。
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公开(公告)号：EP2468287B1
公开(公告)日：2014-04-23
申请号：EP12161047.1
申请日：2009-09-10
发明人： Ku, Yiyin , Or, Yat, Sun , Wagaw, Sable, H. , Engstrom, Ken , Grieme, Tim , Sheikh, Ahmad , Mei, Jianzhang , McDaniel, Keith, F. , Chen, Hui-ju , Shanley, Jason, P. , Kempf, Dale, J. , Grampovnik, David, J. , Sun, Ying , Liu, Dong , Gai, Yonghua , Sun, Ying
IPC分类号： A61K38/00 , A61K38/12 , C07D487/04
CPC分类号： C07K1/113 , C07D487/04
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公开(公告)号：EP2468286B1
公开(公告)日：2014-04-23
申请号：EP12160849.1
申请日：2009-09-10
发明人： Ku, Yiyin , Or, Yat, Sun , Wagaw, Sable, H. , Engstrom, Ken , Grieme, Tim , Sheikh, Ahmad , Mei, Jianzhang , McDaniel, Keith, F. , Chen, Hui-ju , Shanley, Jason, P. , Kempf, Dale, J. , Grampovnik, David, J. , Sun, Ying , Liu, Dong , Gai, Yonghua
IPC分类号： A61K38/00 , A61K38/12 , C07D487/04
CPC分类号： C07K1/113 , C07D487/04
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公开(公告)号：EP2805726B1
公开(公告)日：2018-05-02
申请号：EP14181565.4
申请日：2009-09-10
发明人： Ku, Yiyin , Or, Yat, Sun , Wagaw, Sable, H. , Engstrom, Ken , Grieme, Tim , Sheikh, Ahmad , Mei, Jianzhang , McDaniel, Keith, F. , Chen, Hui-ju , Shanley, Jason, P. , Kempf, Dale, J. , Grampovnik, David, J. , Gai, Yonghua , Sun, Ying , Liu, Dong
IPC分类号： A61K38/00 , A61K38/12 , C07D487/04
CPC分类号： C07K1/113 , C07D487/04
摘要： The present invention relates to novel macrocyclic compounds and methods of use thereof. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
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