公开(公告)号：EP1321146A3

公开(公告)日：2004-06-02

申请号：EP03004941.5

申请日：1999-03-10

申请人： Endorecherche Inc.

发明人： Labrie, Fernand ,  Belanger, Alain ,  Gauthier, Sylvain ,  Luu-The, Van ,  Merand, Yves ,  Poirier, Donald ,  Provencher, Louis ,  Singh, Shankar Mohan

IPC分类号： A61K31/585 ,  A61K45/06 ,  C07J21/00 ,  A61P5/24 ,  A61K31/566 ,  A61K31/5685

CPC分类号： C07J21/00 ,  A61K31/566 ,  A61K31/5685 ,  A61K31/585 ,  A61K45/06 ,  A61K2300/00

摘要： Novel methods of medical treatment and/or inhibition of development of diseases are disclosed for diseases that are sensitive to androgenic or estrogenic activity. The treatments utilize inhibitors of type 5 and/or type 3 17β-hydroxysteroid dehydrogenase. Novel inhibitors of type 5 17β-hydroxysteroid dehydrogenase are also disclosed, as are novel inhibitors of type 3 17β-hydroxysteroid dehydrogenase.

公开(公告)号：EP1321146A2

公开(公告)日：2003-06-25

申请号：EP03004941.5

申请日：1999-03-10

申请人： Endorecherche Inc.

发明人： Labrie, Fernand ,  Belanger, Alain ,  Gauthier, Sylvain ,  Luu-The, Van ,  Merand, Yves ,  Poirier, Donald ,  Provencher, Louis ,  Singh, Shankar Mohan

IPC分类号： A61K31/585 ,  A61K45/06 ,  C07J21/00 ,  A61P5/24

CPC分类号： C07J21/00 ,  A61K31/566 ,  A61K31/5685 ,  A61K31/585 ,  A61K45/06 ,  A61K2300/00

摘要： Novel methods of medical treatment and/or inhibition of development of diseases are disclosed for diseases that are sensitive to androgenic or estrogenic activity. The treatments utilize inhibitors of type 5 and/or type 3 17β-hydroxysteroid dehydrogenase. Novel inhibitors of type 5 17β-hydroxysteroid dehydrogenase are also disclosed, as are novel inhibitors of type 3 17β-hydroxysteroid dehydrogenase.

摘要翻译： 公开了治疗和/或抑制疾病发展的新方法，用于对雄激素或雌激素活性敏感的疾病。 这些治疗方法使用5型和/或3型17β-羟基类固醇脱氢酶的抑制剂。 还公开了5-17型β-羟基类固醇脱氢酶的新型抑制剂，以及317β-羟基类固醇脱氢酶的新型抑制剂。