BIOLOGICALLY ACTIVE FORMULATION BASED ON CYCLODEXTRIN SUPRAMOLECULAR COMPLEXES
    3.
    发明授权
    BIOLOGICALLY ACTIVE FORMULATION BASED ON CYCLODEXTRIN SUPRAMOLECULAR COMPLEXES 有权
    生物活性FROMULIERUNG BASED环糊精超分子复合物

    公开(公告)号:EP1876890B1

    公开(公告)日:2012-08-08

    申请号:EP06754780.2

    申请日:2006-04-21

    申请人: ENDURA S.p.A.

    CPC分类号: A01N25/10

    摘要: The present invention provides a formulation characterized by the simultaneous presence in cyclodextrin based supramolecular complexes, of two components, one of which possesses insecticidal, acaricidal, fungicidal, snailcidal or vermicidal activity and the other possesses an activity synergistic with the first, enhancing its effectiveness. The biologically active substance is chosen from the following classes of chemical products: carbamates, organophosphates, thioureas, pentatomic or hexatomic heterocycles in which 1, 2 or 3 nitrogen atoms are present. The synergistic substance can be chosen from components containing at least one aromatic or non aromatic carbocyclic ring, such as piperonyl butoxide, sesamol, verbutin or MGK 264. For the same dose, the activity of the present formulations is greater than that of the mixture of the two active components alone or separately complexed with cyclodextrin. The process for preparing said formulation and its use for the activities herein indicated are further aspects of the present invention.

    PROCESS FOR SYNTHESISING HELIOTROPINE AND ITS DERIVATIVES
    7.
    发明授权
    PROCESS FOR SYNTHESISING HELIOTROPINE AND ITS DERIVATIVES 有权
    法合成洋茉莉醛及其衍生物

    公开(公告)号:EP1720851B1

    公开(公告)日:2009-03-04

    申请号:EP04817395.9

    申请日:2004-10-28

    申请人: ENDURA S.p.A.

    IPC分类号: C07D317/54

    CPC分类号: C07D317/54

    摘要: A new high-yield, easily industrialized process for synthesising compounds of formula (IV), in which X1 and X2, the same or different, are linear or branched C1-C8 alkyls, n and m are 0,1 or 2, with the proviso that n and m are not simultaneously 0; or (OX1)n and (OX2)m taken together form an O-T-O group where T is chosen from -CH2-, -CH2CH2­, -CH2CH2CH2-, -C(CH3)2-. The process comprises treating a chloromethyl derivative (I) with an alkaline acetate to form the intermediate acetylderivative (II); the intermediate (II) is to hydrolysed to form the alcohol (III); the alcohol (III) is then oxidised in the presence of air and catalysts to obtain the desired derivative (IV). The process runs its course within a short period of time, with high yields and high selectivity; in addition, the process does not require purification and separation of the intermediates and can therefore be favourably conducted in a single batch.

    INSECTICIDAL FORMULATIONS OF MICROCAPSULES
    8.
    发明公开
    INSECTICIDAL FORMULATIONS OF MICROCAPSULES 审中-公开
    杀虫剂配制剂从微观胶囊

    公开(公告)号:EP2871952A1

    公开(公告)日:2015-05-20

    申请号:EP13734100.4

    申请日:2013-07-05

    申请人: Endura S.p.A.

    摘要: Use of formulations consisting of suspo-emulsions comprising a microcapsule suspension, the microcapsules including at least one active ingredient selected from the pyrethroid and/or neonicotinoid classes, at least one synergistic agent, and an emulsion comprising at least an active ingredient of the above classes, and at least one synergistic agent, the microcapsules being formed of polyurea, obtainable by inter-facial polymerization of diphenylmethylen-4,4′-diisocyanate, optionally in admixture with polymethylenpolyphenylisocyanate, the formulations having a prolonged knockdown and killing effect, even of three months, even of six months or even of nine months, the suspo-emulsions comprising: component A): microcapsules in suspension comprising inside the microcapsule at least one active ingredient, a synergistic agent, optionally a solvent, the total amount of these components being not higher than 50% by weight with respect to the weight of the suspension A), the complement to 100% by weight of component A) comprising the polymer of the micro-capsule shell, water and additives; component B): emulsion comprising an amount of at least one active ingredient and one synergistic agent, the amount of active ingredient+synergistic agent being not higher than 50% by weight of the emulsion, of component B) constituted by water, additives, optionally solvents.

    PROCESS FOR SYNTHESISING HELIOTROPINE AND ITS DERIVATIVES
    10.
    发明公开
    PROCESS FOR SYNTHESISING HELIOTROPINE AND ITS DERIVATIVES 有权
    法合成洋茉莉醛及其衍生物

    公开(公告)号:EP1720851A1

    公开(公告)日:2006-11-15

    申请号:EP04817395.9

    申请日:2004-10-28

    申请人: ENDURA S.p.A.

    IPC分类号: C07D317/54

    CPC分类号: C07D317/54

    摘要: A new high-yield, easily industrialized process for synthesising compounds of formula (IV), in which X1 and X2, the same or different, are linear or branched C1-C8 alkyls, n and m are 0,1 or 2, with the proviso that n and m are not simultaneously 0; or (OX1)n and (OX2)m taken together form an O-T-O group where T is chosen from -CH2-, -CH2CH2­, -CH2CH2CH2-, -C(CH3)2-. The process comprises treating a chloromethyl derivative (I) with an alkaline acetate to form the intermediate acetylderivative (II); the intermediate (II) is to hydrolysed to form the alcohol (III); the alcohol (III) is then oxidised in the presence of air and catalysts to obtain the desired derivative (IV). The process runs its course within a short period of time, with high yields and high selectivity; in addition, the process does not require purification and separation of the intermediates and can therefore be favourably conducted in a single batch.