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公开(公告)号:EP3365364A1
公开(公告)日:2018-08-29
申请号:EP16858388.8
申请日:2016-10-21
发明人: LU, Jingwei , YANG, Zhiyuan , LIU, Cheng , LIU, Hong , XU, Yiyang , YAN, Su , CHAN, Vivien Wai-fan , HORAN, Lucas
IPC分类号: C07K14/725 , A61K38/17 , A61K35/17 , C12N15/62 , C12N15/63
CPC分类号: A61K39/39558 , A61K35/17 , A61K38/00 , A61K2039/505 , C07K14/7051 , C07K16/2809 , C07K2317/522 , C07K2317/55 , C07K2317/56 , C07K2317/622 , C07K2317/73 , C07K2319/00 , C07K2319/03 , C07K2319/33 , C07K2319/74 , C12N15/62
摘要: The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM capable of recruiting at least one TCR-associated signaling module. Also provided are methods of making and using these constructs.
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公开(公告)号:EP4003373A1
公开(公告)日:2022-06-01
申请号:EP20843894.5
申请日:2020-07-24
发明人: YUN, Hongruo , CUI, Jun , ZHANG, Pengbo , XU, Yiyang , HORAN, Lucas , XU, Shaohua , XIONG, Guangyan , LI, Shan , XU, Yixiang , HELLER, Bradley Austin , ZHANG, Hongbing , LIU, Hong
IPC分类号: A61K35/17 , C07K14/705 , A61P35/00
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公开(公告)号:EP4004030A1
公开(公告)日:2022-06-01
申请号:EP20843370.6
申请日:2020-07-24
发明人: YUN, Hongruo , CUI, Jun , ZHANG, Pengbo , XU, Yiyang , HORAN, Lucas , XU, Shaohua , XIONG, Guangyan , LI, Shan , XU, Yixiang , LIU, Hong
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4.
公开(公告)号:EP3615046A1
公开(公告)日:2020-03-04
申请号:EP18791852.9
申请日:2018-04-24
发明人: LIU, Hong , ZHANG, Pengbo , HORAN, Lucas , XU, Yiyang , STALEY, Binnaz K. , LIU, Lianxing , YUN, Hongruo
IPC分类号: A61K35/17 , A61P35/00 , C07K14/725 , C07K16/30 , C07K19/00 , C12N5/0783
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公开(公告)号:EP3806904A1
公开(公告)日:2021-04-21
申请号:EP19822284.6
申请日:2019-06-17
发明人: LIU, Hong , YUN, Hongruo , GE, Xiaomei , YANG, Zhiyuan , LIU, Lianxing , ZHANG, Pengbo , XU, Yixiang , LI, Shan , HORAN, Lucas
IPC分类号: A61K39/395 , C07K16/28 , C07K16/30 , C07K16/32
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公开(公告)号:EP3615567A1
公开(公告)日:2020-03-04
申请号:EP18789935.6
申请日:2018-04-24
发明人: HORAN, Lucas , XU, Yiyang , YANG, Zhiyuan , LIU, Hong , MORALES, Javier , LIU, Lianxing
IPC分类号: C07K14/725 , A61K35/17 , A61P35/00 , C07K16/30 , C07K19/00 , C12N5/0783
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