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公开(公告)号：EP1482912A2
公开(公告)日：2004-12-08
申请号：EP03716588.3
申请日：2003-03-14
申请人： Euro-Celtique, S.A.
CPC分类号： A61K9/1617 , A61K9/1676 , A61K9/2009 , A61K9/2054 , A61K9/2077 , A61K9/4858 , A61K9/5078 , A61K31/485
摘要： The present invention relates to compositions and methods of stabilizing naltrexone hydrochloride.
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2.发明授权
公开(公告)号：EP1615615B1
公开(公告)日：2010-02-24
申请号：EP04759980.8
申请日：2004-04-19
申请人： EURO-CELTIQUE S.A.
IPC分类号： A61K9/14 , A61P25/04 , A61K31/485
CPC分类号： A61K9/2081 , A61K9/1617 , A61K9/1635 , A61K9/282 , A61K9/2826 , A61K9/2846 , A61K9/2866 , A61K9/4808 , A61K9/4858 , A61K9/4866 , A61K9/5026 , A61K9/5047 , A61K9/5073 , A61K9/5084 , A61K9/5123 , A61K9/5138 , A61K31/485 , A61K45/06 , A61K2300/00
摘要： Disclosed in certain embodiments is a dosage form comprising a plurality of extruded particles comprising an adverse agent or antagonist and a layer disposed about the particles.
摘要翻译： 在某些实施方案中公开的是包含多个包含不利剂或拮抗剂的挤出颗粒和围绕颗粒设置的层的剂型。
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公开(公告)号：EP1542658A1
公开(公告)日：2005-06-22
申请号：EP03751860.2
申请日：2003-08-15
申请人： Euro-Celtique S.A.
CPC分类号： A61K9/5078 , A61K9/2886 , A61K9/5026 , A61K9/5036 , A61K9/5047 , A61K31/485
摘要： Pharmaceutical compositions containing a therapeutically active agent, a diffusion barrier coating and coating comprising a hydrophobic material.
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公开(公告)号：EP1482912B1
公开(公告)日：2011-05-25
申请号：EP03716588.3
申请日：2003-03-14
申请人： EURO-CELTIQUE S.A.
CPC分类号： A61K9/1617 , A61K9/1676 , A61K9/2009 , A61K9/2054 , A61K9/2077 , A61K9/4858 , A61K9/5078 , A61K31/485
摘要： The present invention relates to compositions and methods of stabilizing naltrexone hydrochloride.
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公开(公告)号：EP1615615A2
公开(公告)日：2006-01-18
申请号：EP04759980.8
申请日：2004-04-19
申请人： Euro-Celtique S.A.
IPC分类号： A61K6/00
CPC分类号： A61K9/2081 , A61K9/1617 , A61K9/1635 , A61K9/282 , A61K9/2826 , A61K9/2846 , A61K9/2866 , A61K9/4808 , A61K9/4858 , A61K9/4866 , A61K9/5026 , A61K9/5047 , A61K9/5073 , A61K9/5084 , A61K9/5123 , A61K9/5138 , A61K31/485 , A61K45/06 , A61K2300/00
摘要： Disclosed in certain embodiments is a dosage form comprising a plurality of extruded particles comprising an adverse agent or antagonist and a layer disposed about the particles.
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公开(公告)号：EP1542658B1
公开(公告)日：2010-12-29
申请号：EP03751860.2
申请日：2003-08-15
申请人： EURO-CELTIQUE S.A.
CPC分类号： A61K9/5078 , A61K9/2886 , A61K9/5026 , A61K9/5036 , A61K9/5047 , A61K31/485
摘要： Pharmaceutical compositions containing a therapeutically active agent, a diffusion barrier coating and coating comprising a hydrophobic material.
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7.发明公开TAMPER RESISTANT DOSAGE FORM COMPRISING CO-EXTRUDED, ADVERSE AGENT PARTICLES AND PROCESS OF MAKING SAME 审中-公开用于生产不想要的与过程的安全剂量共挤粒子
公开(公告)号：EP1615625A2
公开(公告)日：2006-01-18
申请号：EP04760176.0
申请日：2004-04-21
申请人： Euro-Celtique, S.A.
发明人： OSHLACK, Benjamin , HUANG, Hua-Pin
CPC分类号： A61K9/5084 , A61K9/0053 , A61K9/0092 , A61K9/1635 , A61K9/1694 , A61K9/4808 , A61K9/5026 , A61K9/5089 , A61K31/445 , A61K31/485
摘要： The present invention relates to co-extruded pharmaceutical compositions and dosage forms comprising an adverse agent, such as an opioid antagonist, which can be sequestered. The pharmaceutical compositions and dosage forms diversion of a dosage form containing an active pharmaceutical agent, such as an opioid. The present invention also relates to methods of treating a patient with such a dosage form, as well as kits containing such a dosage form with instructions for using the dosage form to treat a patient. The present invention further relates to a process for the preparation of such pharmaceutical compositions and dosage forms comprising co-extrusion of a core comprising an adverse agent and a sheath.
摘要翻译： 本发明涉及共挤出的药物组合物和剂型包含不利剂，作为谋求阿片样物质拮抗剂，其可以被螯合。 含有活性药剂，作为寻求阿片样物质剂型的药物组合物和剂型分流。 因此，本发明涉及一种具有寻求剂型，以及含有寻求的剂型与用于使用该剂型以治疗患者说明书的试剂盒治疗的患者的方法。 本发明还涉及一种用于药物寻求组合物和剂型，其包括芯，其包括不利剂和鞘的共挤出的制备方法。
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公开(公告)号：EP0785775B1
公开(公告)日：2004-01-07
申请号：EP95939928.8
申请日：1995-11-03
申请人： EURO-CELTIQUE S.A.
CPC分类号： A61K9/1635 , A61K9/145 , A61K9/1617 , A61K9/1652 , A61K9/1694 , A61K9/2018 , A61K9/2027 , A61K9/2077 , A61K9/2081 , A61K9/2095 , Y10S514/951 , Y10S514/962
摘要： Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrusion techniques are disclosed.
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公开(公告)号：EP3150228A3
公开(公告)日：2017-06-28
申请号：EP15181540.4
申请日：2004-04-19
申请人： EURO-CELTIQUE S.A.
CPC分类号： A61K9/2081 , A61K9/1617 , A61K9/1635 , A61K9/282 , A61K9/2826 , A61K9/2846 , A61K9/2866 , A61K9/4808 , A61K9/4858 , A61K9/4866 , A61K9/5026 , A61K9/5047 , A61K9/5073 , A61K9/5084 , A61K9/5123 , A61K9/5138 , A61K31/485 , A61K45/06 , A61K2300/00
摘要： Disclosed in certain embodiments is a dosage form comprising a plurality of extruded particles comprising an adverse agent or antagonist and a layer disposed about the particles.
摘要翻译： 在某些实施方案中公开了包含多个挤出颗粒的剂型，所述挤出颗粒包含不利剂或拮抗剂和围绕所述颗粒设置的层。
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公开(公告)号：EP3150228A2
公开(公告)日：2017-04-05
申请号：EP15181540.4
申请日：2004-04-19
申请人： EURO-CELTIQUE S.A.
CPC分类号： A61K9/2081 , A61K9/1617 , A61K9/1635 , A61K9/282 , A61K9/2826 , A61K9/2846 , A61K9/2866 , A61K9/4808 , A61K9/4858 , A61K9/4866 , A61K9/5026 , A61K9/5047 , A61K9/5073 , A61K9/5084 , A61K9/5123 , A61K9/5138 , A61K31/485 , A61K45/06 , A61K2300/00
摘要： Disclosed in certain embodiments is a dosage form comprising a plurality of extruded particles comprising an adverse agent or antagonist and a layer disposed about the particles.
摘要翻译： 在某些实施方案中公开的是包含多个包含不利剂或拮抗剂的挤出颗粒和围绕颗粒设置的层的剂型。
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