DIFFERENTIAL BH3 MITOCHONDRIAL PROFILING
    1.
    发明公开
    DIFFERENTIAL BH3 MITOCHONDRIAL PROFILING 审中-公开
    不同的MITOCHONDRIALE BH3-PROFILIERUNG

    公开(公告)号:EP3022222A1

    公开(公告)日:2016-05-25

    申请号:EP14825933.6

    申请日:2014-07-18

    发明人: CARDONE, Michael

    IPC分类号: C07K14/47

    摘要: The present invention relates to methods of determining cancer cell sensitivity to treatment by correlating the pattern of sensitivity of the cell to a panel of BH3 domain peptides. The invention also provides a method applying an algorithm to said pattern to predict therapeutic efficacy and of monitoring the shift in cell sensitivity to a therapeutic during treatment.

    摘要翻译: 本发明涉及通过将细胞的灵敏度与一组BH3结构域肽相关联来确定癌细胞对治疗的敏感性的方法。 本发明还提供了一种将所述模式应用于所述模式以预测治疗功效并监测治疗期间治疗剂对细胞敏感性的变化的方法。