公开(公告)号：EP2320895A2

公开(公告)日：2011-05-18

申请号：EP09774582.2

申请日：2009-07-02

申请人： Exelixis, Inc.

发明人： BAHCECI, Suleyman ,  CHAN, Bryan ,  CHAN, Diva, Sze-ming ,  CHEN, Jeff ,  FORSYTH, Timothy, Patrick ,  FRANZINI, Maurizio ,  JAMMALAMADAKA, Vasu ,  JEONG, Joon, Won ,  JONES, Lisa, Renee ,  KELLEY, Ryan, Michael ,  KIM, Moon, Hwan ,  LEAHY, James, W. ,  MAC, Morrison, B. ,  NOGUCHI, Robin, Tammie ,  RAO, Pallavi ,  RIDGWAY, Brian, Hugh ,  XU, Wei ,  WANG, Yong

IPC分类号： A61K31/437 ,  A61K31/506 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/5383 ,  A61K31/55 ,  C07D471/04 ,  C07D487/04 ,  C07D487/10 ,  C07D498/04 ,  C07D498/14 ,  C07D491/107 ,  A61P35/00

CPC分类号： C07D487/04 ,  C07D471/04 ,  C07D519/00

摘要： A compound according to Formula I : or a pharmaceutically-acceptable salt thereof, wherein R1, R3, A, B and D are as defined in the specification; pharmaceutical compositions thereof, and methods of use thereof.