公开(公告)号：EP1483381A2

公开(公告)日：2004-12-08

申请号：EP03743925.4

申请日：2003-03-14

申请人： Exonhit Therapeutics S.A.

发明人： BRACCO, Laurent ,  BRINKMAN, Brigitta ,  COIGNARD, Fanny

IPC分类号： C12N9/64

CPC分类号： C12N9/6445

摘要： The invention relates to the field of biology, genetics and medicine. In particular, the invention relates to novel methods of detecting, characterising and/or treating cancer pathologies, such as prostate cancer. The invention also relates to methods of identifying and screening compounds that are active in said pathologies. Furthermore, the invention relates to compounds, genes, cells, plasmids or compositions that are used to carry out the above-mentioned methods. More specifically, the invention outlines the role of variants of human kallikrein-2 and human kallikrein-3, also known as PSA, in the aforementioned pathologies and the uses of same as therapeutic, diagnostic or experimental targets.