公开(公告)号：EP2260113A2

公开(公告)日：2010-12-15

申请号：EP09754074.4

申请日：2009-03-30

申请人： Exonhit Therapeutics S.A.

发明人： JARRIGE-LE PRADO, Anne-Charlotte ,  BEURDELEY, Pascale ,  PALLARES, Diego ,  ROUET, Fabien ,  BRACCO, Laurent

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q1/6837 ,  C12Q2600/106 ,  C12Q2600/158 ,  C12Q2539/105

摘要： The present application relates to the methods and compositions useful for diagnosing Alzheimer’s disease in mammals, particularly humans. The application particularly describes serous markers for Alzheimer’s disease and the uses thereof in methods of diagnosis. The application also relates to the tools and/or kits useful for implementing these methods (reagents, probes, primers, antibodies, chips, cells, etc.) and the preparation and uses thereof. The invention is useful for detecting the presence or development of Alzheimer’s disease in mammals, including during the early phase, and for predicting the effectiveness of Alzheimer’s disease treatment.