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公开(公告)号：EP2240433B1
公开(公告)日：2013-03-20
申请号：EP08869959.0
申请日：2008-12-23
发明人： BUBENDORF, André , GOLDBACH, Pierre , GRASSMANN, Olaf , HENNIG, Michael , SAUER, Ines , TRUSSARDI, René
IPC分类号： C07C231/22 , C07C233/52
CPC分类号： C07C233/52 , C07C231/22
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公开(公告)号：EP2240433A2
公开(公告)日：2010-10-20
申请号：EP08869959.0
申请日：2008-12-23
发明人： BUBENDORF, André , GOLDBACH, Pierre , GRASSMANN, Olaf , HENNIG, Michael , SAUER, Ines , TRUSSARDI, René
IPC分类号： C07C231/22 , C07C233/52
CPC分类号： C07C233/52 , C07C231/22
摘要： The present invention relates to polymorphic forms of Oseltamivir phosphate, especially the (3R,4R,5S)-5-amino-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-ene-carboxylic acid ethyl ester phosphate, which is a potent inhibitor of viral neuraminidase.
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3.发明授权POLYMORPH OF {6,7-BIS(2-METHOXY-ETHOXY)-QUINAZOLIN-4-YL}-(3E) 有权的多晶型{6,7-双（2-甲氧基乙氧基）喹唑啉-4-基} - （3E）
公开(公告)号：EP1597239B1
公开(公告)日：2008-09-17
申请号：EP04710031.8
申请日：2004-02-11
发明人： BUBENDORF, André, Gerard , HENNIG, Michael , HIDBER, Pirmin , RIMMLER, Goesta , ROHRER, Franziska
IPC分类号： C07D239/94 , A61K31/517 , A61P35/00
CPC分类号： A61K31/517 , C07D239/94
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4.发明公开POLYMORPH OF {6,7-BIS(2-METHOXY-ETHOXY)-QUINAZOLIN-4-YL}-(3E) 有权的多晶型{6,7-双（2-甲氧基乙氧基）喹唑啉-4-基} - （3E）
公开(公告)号：EP1597239A1
公开(公告)日：2005-11-23
申请号：EP04710031.8
申请日：2004-02-11
发明人： BUBENDORF, André, Gerard , HENNIG, Michael , HIDBER, Pirmin , RIMMLER, Goesta , ROHRER, Franziska
IPC分类号： C07D239/94 , A61K31/517 , A61P35/00
CPC分类号： A61K31/517 , C07D239/94
摘要： The invention is concerned with a novel polymorph of [6,7-Bis(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)amine hydrochloride. This polymorph exhibits superior properties compared to the previously known forms of [6,7-Bis(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)amine hydrochloride and can be used as medicament for the treatment of hyperproliferative disorders.
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