-
公开(公告)号：EP2178566A1
公开(公告)日：2010-04-28
申请号：EP08784874.3
申请日：2008-07-18
CPC分类号： C07K14/005 , A61K47/6811 , A61K47/6849 , C07K16/2812 , C07K2317/24 , C07K2317/41 , C07K2317/565 , C07K2317/76 , C12N2740/16122
摘要： The current invention is related to a conjugate comprising two or more antifusogenic peptides and an anti-CD4 antibody (mAb CD4) characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of said anti-CD4 antibody and to the pharmaceutical use of said conjugate.
-
2.发明公开
公开(公告)号：EP2496603A1
公开(公告)日：2012-09-12
申请号：EP10779694.8
申请日：2010-11-04
CPC分类号： C07K16/18 , C07K16/00 , C07K16/32 , C07K16/468 , C07K2317/41 , C07K2317/52 , C07K2318/20 , C07K2319/00 , C07K2319/21 , C07K2319/30
摘要： Herein are reported glycosylated repeat-motif-molecule conjugate of the following formula: (repeat-motif-molecule−linkern)m−conjugation partner−(linkero−repeat-motif-molecule)p, wherein n and o are independently of each other and independently for each value of m and p integer values of 0 or 1, and m and p are independently of each other integer values of 0 or 1 or 2 or 3 or 4 or 5 or 6 or 7, and wherein the repeat-motif-molecule conjugate comprises at least one oligosaccharide attached to a glycosylation site. Also reported are encoding nucleic acids and method for producing these repeat-motif-conjugates in mammalian cells.
摘要翻译： 本文报导了下式的糖基化重复 - 基序 - 分子结合物：（重复 - 基序 - 分子连接）m-缀合配偶体（连接重复 - 基序 - 分子）p，其中n和o彼此独立地为 对于m和p整数值为0或1的每个值独立地为m和p彼此独立地为0或1或2或3或4或5或6或7的整数，并且其中重复 - 分子结合物包含至少一个连接于糖基化位点的寡糖。 还报道了编码核酸和在哺乳动物细胞中产生这些重复基序缀合物的方法。
-
公开(公告)号：EP2496603B1
公开(公告)日：2018-07-18
申请号：EP10779694.8
申请日：2010-11-04
CPC分类号： C07K16/18 , C07K16/00 , C07K16/32 , C07K16/468 , C07K2317/41 , C07K2317/52 , C07K2318/20 , C07K2319/00 , C07K2319/21 , C07K2319/30
摘要： Herein are reported glycosylated repeat-motif-molecule conjugate of the following formula: (repeat-motif-molecule−linkern)m−conjugation partner−(linkero−repeat-motif-molecule)p, wherein n and o are independently of each other and independently for each value of m and p integer values of 0 or 1, and m and p are independently of each other integer values of 0 or 1 or 2 or 3 or 4 or 5 or 6 or 7, and wherein the repeat-motif-molecule conjugate comprises at least one oligosaccharide attached to a glycosylation site. Also reported are encoding nucleic acids and method for producing these repeat-motif-conjugates in mammalian cells.
-
公开(公告)号：EP2054086A1
公开(公告)日：2009-05-06
申请号：EP07801642.5
申请日：2007-08-14
发明人： BRANDT, Michael , FISCHER, Stephan , KOPETZKI, Erhard , SANKURATRI, Suryanarayana , SCHUMACHER, Ralf
IPC分类号： A61K47/48
CPC分类号： C07K16/2866 , A61K47/6811 , A61K47/6849 , C07K16/2812 , C07K2317/24 , C07K2317/41 , C12N2740/16033 , C12N2740/16122
摘要： The current invention is related to a conjugate comprising one or more antifusogenic peptides and an antibody against an HIV gp120 binding cell surface receptor, characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of said antibody against an HIV gp120 binding cell surface receptor and to the pharmaceutical use of said conjugate.
-
-
-
搜索结果
4 条记录 (耗时 0.013 秒)
