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1.
公开(公告)号:EP1501815A1
公开(公告)日:2005-02-02
申请号:EP03749855.7
申请日:2003-04-14
发明人: CORBETT, Wendy, Lea , GRIMSBY, Joseph, Samuel , HAYNES, Nancy-Ellen , KESTER, Robert, Francis , MAHANEY, Paige, Erin , RACHA, Jagdish, Kumar , SARABU, Ramakanth , WANG, Ka
IPC分类号: C07D307/16 , C07D309/04 , C07D417/12 , C07D405/12 , C07D241/20 , C07D409/12 , C07D277/46 , C07D213/75 , C07C275/52 , A61K31/335 , A61K31/38 , A61K31/425 , A61K31/4965 , A61K31/44 , A61P3/10
CPC分类号: C07D213/75 , C07C275/50 , C07C2601/08 , C07D241/20 , C07D277/46 , C07D307/16 , C07D309/04 , C07D405/12 , C07D409/12 , C07D417/12
摘要: Compounds of the formula (I); wherein formula (II) represents a substituted group, an oxa-cycloalkyl group or a thia-cycloalkyl group, are glucokinase activators useful in the treatment of type II diabetes.
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2.SUBSTITUTED PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS 有权
标题翻译: VERWENDUNG ALS GLUCOKINASEAKTIVATOREN的替代苯乙烯胺公开(公告)号:EP1501815B1
公开(公告)日:2006-11-22
申请号:EP03749855.7
申请日:2003-04-14
发明人: CORBETT, Wendy, Lea , GRIMSBY, Joseph, Samuel , HAYNES, Nancy-Ellen , KESTER, Robert, Francis , MAHANEY, Paige, Erin , RACHA, Jagdish, Kumar , SARABU, Ramakanth , WANG, Ka
IPC分类号: C07D307/16 , C07D309/04 , C07D417/12 , C07D405/12 , C07D241/20 , C07D409/12 , C07D277/46 , C07D213/75 , C07C275/52 , A61K31/335 , A61K31/38 , A61K31/425 , A61K31/4965 , A61K31/44 , A61P3/10
CPC分类号: C07D213/75 , C07C275/50 , C07C2601/08 , C07D241/20 , C07D277/46 , C07D307/16 , C07D309/04 , C07D405/12 , C07D409/12 , C07D417/12
摘要: Compounds of the formula (I); wherein formula (II) represents a substituted group, an oxa-cycloalkyl group or a thia-cycloalkyl group, are glucokinase activators useful in the treatment of type II diabetes.
摘要翻译: 2,3-二取代的N-杂芳族丙酰胺,其中2-取代为取代苯基,3-位是极性环,所述丙酰胺是葡萄糖激酶活化剂,其在II型治疗中增加胰岛素分泌 糖尿病。
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