公开(公告)号：EP1888571A2

公开(公告)日：2008-02-20

申请号：EP06724997.9

申请日：2006-03-09

申请人： F. Hoffmann-La Roche AG

发明人： ABRECHT, Stefan ,  BUBENDORF, André, Gérard ,  GOETZOE, Stephan ,  GRASSMANN, Olaf ,  MONTAVON, Francois ,  MOOG, Regina ,  ROHRER, Franziska ,  RUF, Armin ,  SCALONE, Michelangelo ,  SCHWITTER, Urs ,  WANG, Shaoning

IPC分类号： C07D413/12 ,  A61K31/422 ,  A61P3/04 ,  A61P3/10

CPC分类号： C07D413/12

摘要： The invention is concerned with (S)-l-{[2-(5-Methyl-2-phenyl-oxazol-4-yl)- ethylamino]-acetyl}-pyrrolidine-2-carbonitrile mesylate and crystalline polymorphs of this compound. This compound and its polymorphic forms exhibits superior properties compared to the previously known compounds and can be used as medicament for the treatment of disorders which are associated with DPP-IV.