公开(公告)号：EP1924579B1

公开(公告)日：2011-02-09

申请号：EP06778310.0

申请日：2006-08-21

申请人： F.Hoffmann-La Roche AG

发明人： BINGGELI, Alfred ,  CHRIST, Andreas, D. ,  GREEN, Luke ,  GUBA, Wolfgang ,  MAERKI, Hans, P. ,  MARTIN, Rainer, E. ,  MOHR, Peter

IPC分类号： C07D413/12 ,  C07D413/14 ,  C07D498/04 ,  C07D417/12 ,  C07D417/14 ,  A61P3/10 ,  A61P3/04 ,  A61P17/06 ,  A61P19/02 ,  A61K31/428 ,  A61K31/437 ,  A61K31/423

CPC分类号： C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14

摘要： This invention is concerned with compounds of the formula (I) wherein X, A, B, R1, R2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to then- use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

公开(公告)号：EP1924579A2

公开(公告)日：2008-05-28

申请号：EP06778310.0

申请日：2006-08-21

申请人： F.HOFFMANN-LA ROCHE AG

发明人： BINGGELI, Alfred ,  CHRIST, Andreas, D. ,  GREEN, Luke ,  GUBA, Wolfgang ,  MAERKI, Hans, P. ,  MARTIN, Rainer, E. ,  MOHR, Peter

IPC分类号： C07D413/12 ,  C07D413/14 ,  C07D498/04 ,  C07D417/12 ,  C07D417/14 ,  A61P3/10 ,  A61P3/04 ,  A61P17/06 ,  A61P19/02 ,  A61K31/428 ,  A61K31/437 ,  A61K31/423

CPC分类号： C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14

摘要： This invention is concerned with compounds of the formula (I) wherein X, A, B, R1, R2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to then- use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

摘要翻译： 本发明涉及其中X，A，B，R1，R2和G如说明书和权利要求书中所定义的式（I）化合物及其药学上可接受的盐。 本发明进一步涉及含有这些化合物的药物组合物，其制备方法，然后用于治疗和/或预防与调节SST受体亚型5相关的疾病。