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公开(公告)号：EP4013862A2
公开(公告)日：2022-06-22
申请号：EP20810983.5
申请日：2020-11-25
申请人： Firmenich SA
发明人： WANG, Qi , SCHALK, Michel
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公开(公告)号：EP1893753B1
公开(公告)日：2015-12-23
申请号：EP06756090.4
申请日：2006-06-08
申请人： FIRMENICH SA
发明人： SCHALK, Michel
IPC分类号： C12N9/00
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公开(公告)号：EP3303599A1
公开(公告)日：2018-04-11
申请号：EP16776159.2
申请日：2016-04-11
申请人： Firmenich SA
发明人： SCHALK, Michel , DEGUERRY, Fabienne , LI, Pan , HE, Xiufeng , WANG, Qi
CPC分类号： C12P5/007 , C12N9/88 , C12Y402/03039 , C12Y402/03079
摘要： Provided herein is an isolated polypeptide from Juniperus virginiana, Platycladus orientalis ‘Beverleyensis’ or Platycladus orientalis comprising a (+)-cedrol or a (−)-thujopsene synthase. Further provided herein is an isolated nucleic acid molecule from Juniperus virginiana, Platycladus orientalis ‘Beverleyensis’ or Platycladus orientalis encoding a (+)-cedrol or (−)-thujopsene synthase. Further provided herein are methods of producing (+)-cedrol or (−)-thujopsene.
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公开(公告)号：EP2800818A1
公开(公告)日：2014-11-12
申请号：EP12801747.2
申请日：2012-12-17
申请人： Firmenich SA
发明人： NIELSEN, Jens , SIEWERS, Verena , CHEN, Yun , DAVIET, Laurent , SCHALK, Michel
CPC分类号： C12N15/81 , C12N9/0006 , C12N9/0008 , C12N9/1025 , C12N9/1029 , C12N9/93 , C12P5/007 , C12P7/16 , C12P7/625 , C12Y101/01002 , C12Y102/01004 , C12Y203/01009 , C12Y602/01001 , Y02E50/10
摘要： The present invention relates to yeast cells producing high levels of acetoacetyl-CoA. It also relates to a method for making such yeast cells and to the use of such yeastcells in a method for producing acetyl-CoA derived products.
摘要翻译： 本发明涉及产生高水平乙酰乙酰辅酶A的酵母细胞。 本发明还涉及一种制备这种酵母细胞的方法以及这种酵母细胞在生产乙酰辅酶A衍生产物的方法中的用途。
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6.发明公开
公开(公告)号：EP2773751A1
公开(公告)日：2014-09-10
申请号：EP12778111.0
申请日：2012-10-25
申请人： Firmenich SA
发明人： SCHALK, Michel , DEGUERRY, Fabienne
CPC分类号： C12P5/007 , C12N9/0071 , C12P7/02 , C12P7/24 , C12P7/40
摘要： The present invention provides the nucleic acid and the amino acid sequences of a cytochrome P450 capable of oxidizing terpene molecules. It also provides a method of oxidizing terpene molecules comprising contacting the cytochrome P450 of the invention with the terpene molecule intended to be oxidized. In particular, said method may be carried out in vitro or in vivo to produce oxidized terpene molecules, which may be used in different technical fields such as for example perfumery and flavoring. The present invention also provides an expression vector containing the nucleic acid. A non-human host organism or a cell transformed with the nucleic acid is also an object of the invention.
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7.发明公开MODIFIED MICROORGANISMS AND USE THEREOF FOR TERPENE PRODUCTION 有权改编自MIERROORGANISMEN UND IHRE VERWENDUNG BEI DER HERSTELLUNG VON TERPEN
公开(公告)号：EP2723870A1
公开(公告)日：2014-04-30
申请号：EP12731321.1
申请日：2012-06-01
申请人： Firmenich SA
发明人： DAVIET, Laurent , SCHALK, Michel , NIELSEN, Jens , SIEWERS, Verena , KNUF, Christoph , SCALCINATI, Gionata
CPC分类号： C12P5/026 , C12N9/1085 , C12N9/88 , C12N15/635 , C12N15/81 , C12P5/002 , C12P5/007 , C12P5/02
摘要： The present invention relates to the control of gene expression by a heterologous glucose-regulated promoter, to microorganisms in which gene expression is controlled by a heterologous glucose-regulated promoter and to methods using said microorganisms for the production of terpenes during glucose-limited fed-batch fermentation.
摘要翻译： 本发明涉及通过异源葡萄糖调节启动子对基因表达由异源葡萄糖调节的启动子控制的微生物的控制，以及使用所述微生物在葡萄糖限制性补料启动子中产生萜烯的方法， 分批发酵。
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公开(公告)号：EP3997215A1
公开(公告)日：2022-05-18
申请号：EP20735630.4
申请日：2020-07-08
申请人： Firmenich SA
发明人： SCHALK, Michel , DEGUERRY, Fabienne , SOLIS ESCALANTE, Daniel , BECCUCCI, Sabine , ANZIANI, Pauline
IPC分类号： C12N9/02
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公开(公告)号：EP3697898A1
公开(公告)日：2020-08-26
申请号：EP19700715.6
申请日：2019-01-16
申请人： Firmenich SA
IPC分类号： C12N9/02
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