公开(公告)号：EP3215153A4

公开(公告)日：2018-01-24

申请号：EP15857812

申请日：2015-11-05

申请人： FLEXUS BIOSCIENCES INC

发明人： BECK HILARY PLAKE ,  JAEN JUAN CARLOS ,  OSIPOV MAKSIM ,  POWERS JAY PATRICK ,  REILLY MAUREEN KAY ,  SHUNATONA HUNTER PAUL ,  WALKER JAMES ROSS ,  ZIBINSKY MIKHAIL ,  BALOG JAMES AARON ,  WILLIAMS DAVID K ,  MARKWALDER JAY A ,  CHERNEY EMILY CHARLOTTE ,  SHAN WEIFANG ,  HUANG AUDRIS

IPC分类号： A61K31/4375 ,  A61K31/4709 ,  A61K31/496 ,  C07D215/14 ,  C07D215/233 ,  C07D217/04 ,  C07D231/56 ,  C07D239/74 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D471/04 ,  C07D487/04

CPC分类号： C07D487/04 ,  A61K31/416 ,  A61K31/437 ,  A61K31/4375 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/506 ,  A61K31/517 ,  A61K31/519 ,  A61K45/06 ,  C07D215/06 ,  C07D215/14 ,  C07D215/233 ,  C07D217/04 ,  C07D231/56 ,  C07D239/74 ,  C07D401/12 ,  C07D401/14 ,  C07D405/08 ,  C07D405/12 ,  C07D417/08 ,  C07D417/12 ,  C07D471/04

摘要： Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.