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    VERFAHREN UND VORRICHTUNG ZUM SELEKTIVEN NACHWEIS FERROMAGNETISCHER ODER SUPERPARAMAGNETISCHER PARTIKEL
    1.
    发明公开
    VERFAHREN UND VORRICHTUNG ZUM SELEKTIVEN NACHWEIS FERROMAGNETISCHER ODER SUPERPARAMAGNETISCHER PARTIKEL 审中-公开
    方法和装置选择性检测FERRO磁性或超顺磁性粒子

    公开(公告)号：EP1597573A1

    公开(公告)日：2005-11-23

    申请号：EP04706604.8

    申请日：2004-01-30

    申请人： FORSCHUNGSZENTRUM JÜLICH GMBH ,  Miehte, Peter

    发明人： MIETHE, Peter ,  KRAUSE, Hans-Joachim ,  ZHANG, Yi ,  WOLTERS, Norbert ,  PLAKSIN, Dmitry

    IPC分类号： G01N27/74 ,  G01N33/543

    CPC分类号： G01N27/745

    摘要： The invention relates to a method for selectively detecting and/or quantifying superparamagnetic and/or ferromagnetic particles on analytes. The method is characterized in that a frequency component of magnetic fields (15, 18), which is generated due to the non-linearity of the magnetization characteristic curve of the particles, is measured at a mixing frequency. A device for selectively detecting and/or quantifying superparamagnetic and/or ferromagnetic particles on analytes comprises: a container (12) that contains particles, which are to be detected and/or quantified, on analytes; at least one oscillator (13, 16; 25) for generating frequencies of alternating magnetic fields (15, 18); at least one field generator (14, 17) for subjecting the analytes to alternating magnetic fields (15, 18); a magnetic field sensor (20) for measuring a response magnetic field (19) of the particles, and; at least one phase-sensitive detector (21, 23). These elements are configured in such a manner as to enable a frequency component of the magnetic fields (15, 18), which is generated due to the non-linearity of the magnetization characteristic curve of the particles, to be measured at a mixing frequency.

    VORRICHTUNG UND VERFAHREN ZUR MESSUNG BIOLOGISCHER UND ELEKTRONISCHER EIGENSCHAFTEN EINER PROBE
    3.
    发明公开
    VORRICHTUNG UND VERFAHREN ZUR MESSUNG BIOLOGISCHER UND ELEKTRONISCHER EIGENSCHAFTEN EINER PROBE 审中-公开
    装置和方法用于样品的测量生物与导电性能

    公开(公告)号：EP2092319A1

    公开(公告)日：2009-08-26

    申请号：EP07817752.4

    申请日：2007-10-31

    申请人： Forschungszentrum Jülich GmbH

    发明人： INGEBRANDT, Sven ,  WOLTERS, Norbert ,  WROBEL, Günter ,  BOUSACK, Herbert ,  OFFENHÄUSSER, Andreas

    IPC分类号： G01N27/414 ,  G01N33/487

    CPC分类号： G01N33/48728 ,  G01N27/414

    摘要： The invention relates to an apparatus and a method for measuring biological characteristics of a sample, the sample being in contact with the gate of a field-effect transistor. According to the invention, an AC voltage is applied to the sample. The nature of the sample then governs the extent to which charges are transferred to the gate. The presence of such charges can be tested using the field-effect transistor, for example using a source-drain current. The invention can be used to measure the response of a biological sample to an AC voltage at zero current and therefore very much more sensitively than by using impedance measurements based on the prior art, in which small currents are to be measured. It is possible to examine single cells or else portions of cells, the prior art having been able to attain a sufficiently large signal only on cell complexes containing a large number of cells.

    RF-SQUID MAGNETOMETER
    9.
    发明公开
    RF-SQUID MAGNETOMETER 有权
    RF-SQUID磁力计

    公开(公告)号：EP1358501A2

    公开(公告)日：2003-11-05

    申请号：EP02708198.3

    申请日：2002-02-02

    申请人： FORSCHUNGSZENTRUM JÜLICH GMBH

    发明人： ZHANG, Yi ,  WOLTERS, Norbert ,  BANZET, Marko ,  ZANDER, Willi ,  SCHUBERT, Jürgen

    IPC分类号： G01R33/035

    CPC分类号： G01R33/0354

    摘要： The invention relates to a system for measuring magnetic flows. Said system comprises a substrate (3) which has a high dielectric constant and is placed between the SQUID (1) and the reading loop (2). Advantageously, the substrate consists of SrTi03 having a dielectric constant ε of approximately 2000 at a temperature of 77 K. Said substrate thus acts as a resonator which advantageously absorbs the radiated rf-energy. The operating point of the SQUID is significantly more stable than in a corresponding coplanar system, and the sensitivity reached of the HTSL-SQUID is advantageously increased.