公开(公告)号：EP3796001A1

公开(公告)日：2021-03-24

申请号：EP19804276.4

申请日：2019-05-17

申请人： FUJIFILM Wako Pure Chemical Corporation ,  HIROSAKI UNIVERSITY

发明人： OHYAMA, Chikara ,  YONEYAMA, Tohru ,  TOBISAWA, Yuki ,  ISHIKAWA, Tomokazu ,  DATE, Mutsuhiro ,  NAKAMURA, Kenji

IPC分类号： G01N33/574 ,  C07K14/42 ,  C07K16/18 ,  C12N15/09

摘要： An object of the present invention is to provide a novel determination method which is capable of determining prostate carcinoma with a higher biopsy avoidance rate.
The present invention relates to a method for determining prostate carcinoma, including obtaining a ratio 1 between an amount of a free prostate specific antigen and an amount of a free PSA having an α(2,3) glycan, the free PSA having an α(2,3) glycan being a free prostate specific antigen having a glycan in which a terminal sialic acid residue of the glycan is α(2,3)-linked to a second galactose residue from a terminal of the glycan, in a sample derived from a subject; obtaining a ratio 2 between the ratio 1 and a volume of the prostate of the subject; and determining prostate carcinoma based on the obtained ratio 2.