摘要:
PCT No. PCT/JP92/00894 Sec. 371 Date Jan. 24, 1994 Sec. 102(e) Date Jan. 24, 1994 PCT Filed Jul. 14, 1992 PCT Pub. No. WO93/02203 PCT Pub. Date Feb. 4, 1993.A new FR901451 substance which is produced by culturing a FR901451 substance-producing strain of the genus Flexibacter in a nutrient medium, this new substance possessing a human leukocyte elastase-inhibiting activity.