公开(公告)号：EP3068423A1

公开(公告)日：2016-09-21

申请号：EP14803025.7

申请日：2014-11-11

申请人： Finzi, Eric ,  Rosenthal, Norman E.

发明人： Finzi, Eric ,  Rosenthal, Norman E.

IPC分类号： A61K38/48 ,  A61K31/00 ,  A61P25/00

CPC分类号： A61K38/4893 ,  A61K31/5513 ,  A61K45/06 ,  C12Y304/24069 ,  A61K2300/00

摘要： Methods are disclosed for treating social anxiety disorder, obsessive compulsive disorder, and/or panic disorder in a subject. The methods include administering a therapeutically effective amount of a neurotoxin to a corrugator supercilli and/or a procerus muscle of the subject to cause paralysis of the corrugator supercilli and/or a procerus muscle in the subject, thereby treating PTSD. The neurotoxin can be Botulinum toxin A, such as at a dose of about 20 to about 50 units of Botulinum toxin A.

摘要翻译： 公开了用于治疗受试者中的社会焦虑症，强迫症和/或恐慌症的方法。 所述方法包括将治疗有效量的神经毒素施用于受试者的波纹矫正器supercilli和/或procerus肌肉，导致受试者中的波纹矫正器supercilli和/或procerus肌肉麻痹，从而治疗PTSD。 神经毒素可以是肉毒杆菌毒素A，例如约20至约50单位的肉毒杆菌毒素A.

公开(公告)号：EP2919807A1

公开(公告)日：2015-09-23

申请号：EP13855449.8

申请日：2013-11-15

申请人： Finzi, Eric ,  Rosenthal, Norman E.

发明人： Finzi, Eric ,  Rosenthal, Norman E.

IPC分类号： A61K39/08

CPC分类号： A61K38/4893 ,  A61K9/0019 ,  A61K45/06 ,  C12Y304/24069 ,  G09B7/06 ,  A61K2300/00

摘要： Methods are disclosed for treating post traumatic stress disorder (PTSD) in a subject. The methods include administering a therapeutically effective amount of a neurotoxin to a corrugator supercilli and/or a procerus muscle of the subject to cause paralysis of the corrugator supercilli and/or a procerus muscle in the subject, thereby treating PTSD. The neurotoxin can be Botulinum toxin A, such as at a dose of about 20 to about 50 units of Botulinum toxin A.

公开(公告)号：EP2919807B1

公开(公告)日：2018-07-11

申请号：EP13855449.8

申请日：2013-11-15

申请人： Finzi, Eric ,  Rosenthal, Norman E.

发明人： Finzi, Eric ,  Rosenthal, Norman E.

IPC分类号： A61K39/08 ,  A61K38/48 ,  A61K45/06 ,  A61P25/00

CPC分类号： A61K38/4893 ,  A61K9/0019 ,  A61K45/06 ,  C12Y304/24069 ,  G09B7/06 ,  A61K2300/00

摘要： Methods are disclosed for treating post traumatic stress disorder (PTSD) in a subject. The methods include administering a therapeutically effective amount of a neurotoxin to a corrugator supercilli and/or a procerus muscle of the subject to cause paralysis of the corrugator supercilli and/or a procerus muscle in the subject, thereby treating PTSD. The neurotoxin can be Botulinum toxin A, such as at a dose of about 20 to about 50 units of Botulinum toxin A.