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公开(公告)号：EP1819352B1
公开(公告)日：2012-09-05
申请号：EP05764528.5
申请日：2005-07-21
发明人： HENRIQUES, Maria das Graças Muller de Oliveira , MONTEIRO, Carmem Penido , SIANI, Antonio Carlos , GUILHERMINO, Jislaine de Fátima , RAMOS, Mônica Freiman de Souza , SAMPAIO, André Luiz Franco , ROSAS, Elaine Cruz , DE LIMA, Lucilene Azevedo , PENNAFORTE, Renato Jabour
CPC分类号： A61K9/0014 , A61K9/0095 , A61K36/58 , A61K47/08 , A61K47/44 , A61K2300/00
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公开(公告)号：EP1819352A1
公开(公告)日：2007-08-22
申请号：EP05764528.5
申请日：2005-07-21
发明人： HENRIQUES, Maria das Graças Muller de Oliveira , MONTEIRO, Carmem Penido , SIANI, Antonio Carlos , GUILHERMINO, Jislaine de Fátima , RAMOS, Mônica Freiman de Souza , SAMPAIO, André Luiz Franco , ROSAS, Elaine Cruz , DE LIMA, Lucilene Azevedo , PENNAFORTE, Renato Jabour
IPC分类号： A61K36/18
CPC分类号： A61K9/0014 , A61K9/0095 , A61K36/58 , A61K47/08 , A61K47/44 , A61K2300/00
摘要： The invention refers to pharmaceutical compositions based on oil extracted from the seeds of Carapa Guianensis Aublet and/or of chemical compounds isolated from this oil and responsible for its biological activity, the tetranortriterpenoids, presenting the following pharmacological activities: anti-allergenic, anti-inflammatory, analgesic and immune modulating with reduced side effects and low cost. Such pharmaceutical compositions of this invention are aimed at the treatment, or prevention, or inhibition of allergenic an inflammatory conditions in human beings, through oral or topic use. In each one of these cases, the composition can be in the liquid or solid form. Compounds for topic use of this invention are atoxic, or with low toxicity, and, specially, provided in the semi-solid form (cream). The pharmaceutical compositions of this invention constitute an important therapeutic alternative for cutaneous and respiratory allergies, besides acting in different inflammatory reactions of allergenic origin or infectious origin. Therefore, these compositions are also used in the symptomatic treatment of rheumatic, inflammatory and degenerative processes, diverse traumas, pain and post surgery inflammation, acute painful syndromes, among others and it can be orally or topically administered.
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