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公开(公告)号：EP4275700A2
公开(公告)日：2023-11-15
申请号：EP23184700.5
申请日：2020-05-11
发明人： Hill, Adrian Vivian Sinton , Bettencourt, Paulo Jorge Goncalves de , Spencer, Alexandra Jane , Ternette, Nicola Maria Nathalie , Salman, Ahmed Mahmoud Ahmed Ahmed , Junqueira, Caroline Furtado , Gazzinelli, Ricardo Tostes , Barbosa, Camila Raquel Rodrigues
IPC分类号： A61K39/015
摘要： An immunogenic composition comprising: a) one or more plasmodium-derived ribosomal or ribosomal associated protein or immunogenic fragment thereof which has a sequence which is at least about 80%, 85%, 90%, 95%, 98%, 99% or 100% identical to a ribosomal or ribosomal associated protein or an immunogenic fragment of a ribosomal or ribosomal associated protein recited in Figure 1; or a ribosomal or ribosomal associated protein or peptide or immunogenic fragment thereof as recited in Figure 2 or Figure 3; and/or b) a polynucleotide encoding one or more protein, peptide or immunogenic fragment of a); wherein the immunogenic composition is for use in eliciting an immune response in a subject to treat or prevent malaria. Also provided are
plasmodium-derived ETRAMPs and/or histones, or immunogenic fragments thereof, for use in eliciting an immune response in a subject, preferably to treat or prevent malaria.-
公开(公告)号：EP4275700A3
公开(公告)日：2024-02-28
申请号：EP23184700.5
申请日：2020-05-11
发明人： Hill, Adrian Vivian Sinton , Bettencourt, Paulo Jorge Goncalves de , Spencer, Alexandra Jane , Ternette, Nicola Maria Nathalie , Salman, Ahmed Mahmoud Ahmed Ahmed , Junqueira, Caroline Furtado , Gazzinelli, Ricardo Tostes , Barbosa, Camila Raquel Rodrigues
IPC分类号： A61K39/015 , A61P33/06
摘要： An immunogenic composition comprising: a) one or more plasmodium-derived ribosomal or ribosomal associated protein or immunogenic fragment thereof which has a sequence which is at least about 80%, 85%, 90%, 95%, 98%, 99% or 100% identical to a ribosomal or ribosomal associated protein or an immunogenic fragment of a ribosomal or ribosomal associated protein recited in Figure 1; or a ribosomal or ribosomal associated protein or peptide or immunogenic fragment thereof as recited in Figure 2 or Figure 3; and/or b) a polynucleotide encoding one or more protein, peptide or immunogenic fragment of a); wherein the immunogenic composition is for use in eliciting an immune response in a subject to treat or prevent malaria. Also provided are
plasmodium-derived ETRAMPs and/or histones, or immunogenic fragments thereof, for use in eliciting an immune response in a subject, preferably to treat or prevent malaria.-
公开(公告)号：EP4265271A3
公开(公告)日：2024-02-21
申请号：EP23184802.9
申请日：2020-05-11
发明人： Hill, Adrian Vivian Sinton , Bettencourt, Paulo Jorge Goncalves de , Spencer, Alexandra Jane , Ternette, Nicola Maria Nathalie , Salman, Ahmed Mahmoud Ahmed Ahmed , Junqueira, Caroline Furtado , Gazzinelli, Ricardo Tostes , Barbosa, Camila Raquel Rodrigues
IPC分类号： A61K39/015
摘要： An immunogenic composition comprising: a) one or more plasmodium-derived ribosomal or ribosomal associated protein or immunogenic fragment thereof which has a sequence which is at least about 80%, 85%, 90%, 95%, 98%, 99% or 100% identical to a ribosomal or ribosomal associated protein or an immunogenic fragment of a ribosomal or ribosomal associated protein recited in Figure 1; or a ribosomal or ribosomal associated protein or peptide or immunogenic fragment thereof as recited in Figure 2 or Figure 3; and/or b) a polynucleotide encoding one or more protein, peptide or immunogenic fragment of a); wherein the immunogenic composition is for use in eliciting an immune response in a subject to treat or prevent malaria. Also provided are plasmodium-derived ETRAMPs and/or histones, or immunogenic fragments thereof, for use in eliciting an immune response in a subject, preferably to treat or prevent malaria.
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公开(公告)号：EP4265271A2
公开(公告)日：2023-10-25
申请号：EP23184802.9
申请日：2020-05-11
发明人： Hill, Adrian Vivian Sinton , Bettencourt, Paulo Jorge Goncalves de , Spencer, Alexandra Jane , Ternette, Nicola Maria Nathalie , Salman, Ahmed Mahmoud Ahmed Ahmed , Junqueira, Caroline Furtado , Gazzinelli, Ricardo Tostes , Barbosa, Camila Raquel Rodrigues
IPC分类号： A61K39/015
摘要： An immunogenic composition comprising: a) one or more plasmodium-derived ribosomal or ribosomal associated protein or immunogenic fragment thereof which has a sequence which is at least about 80%, 85%, 90%, 95%, 98%, 99% or 100% identical to a ribosomal or ribosomal associated protein or an immunogenic fragment of a ribosomal or ribosomal associated protein recited in Figure 1; or a ribosomal or ribosomal associated protein or peptide or immunogenic fragment thereof as recited in Figure 2 or Figure 3; and/or b) a polynucleotide encoding one or more protein, peptide or immunogenic fragment of a); wherein the immunogenic composition is for use in eliciting an immune response in a subject to treat or prevent malaria. Also provided are plasmodium-derived ETRAMPs and/or histones, or immunogenic fragments thereof, for use in eliciting an immune response in a subject, preferably to treat or prevent malaria.
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