专利检索 ap:("G.D. Searle LLC.") AND inv:"DWEK, Raymond A." 第 1 页

1.

发明授权
USE OF (N)-SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS IN COMBINATION THERAPY FOR TREATING HEPATITIS VIRUS INFECTIONS 失效
标题翻译：引起N-取代-1,5-二脱氧-1,5-亚氨基-D-山梨醇化合物在肝炎病毒感染的联合治疗

公开(公告)号：EP1007058B1

公开(公告)日：2005-05-18

申请号：EP98906475.3

申请日：1998-02-12

申请人： G.D. Searle LLC.

发明人： JACOB, Gary, S. , BLOCK, Timothy, M. , DWEK, Raymond A.

IPC分类号： A61K31/70 , A61K31/445

CPC分类号： A61K45/06 , A61K31/445 , A61K31/70

摘要： Provided are methods and compositions for treating hepatitis virus infections in mammals, especially humans. The methods comprise (1) administering N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds in combination with nucleoside antiviral agents, nucleotide antiviral agents, mixtures thereof, or immunomodulating/immunostimulating agents, or (2) administering N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds in combination with nucleoside antivirals agents, nucleotide antiviral agents, or mixtures thereof, and immunomodulating/immunostimulating agents.