公开(公告)号：EP2681177A1

公开(公告)日：2014-01-08

申请号：EP12707289.0

申请日：2012-03-01

申请人： GE Healthcare Limited

发明人： BETTS, Helen, May ,  KHAN, Imtiaz ,  ROBINS, Edward, George

IPC分类号： C07B59/00 ,  C07D213/61

CPC分类号： C07B59/002 ,  C07D213/61 ,  C07D213/81 ,  C07D295/135

摘要： Provided by the present invention is a novel method for obtaining an 18F-labelled compound wherein said compound comprises an 18F-labelled pyridyl ring. The method of the invention is advantageous over the prior art methods as it provides these compounds in higher radiochemical yields than have been possible with previous methods. Also provided by the present invention is an 18F-labelled synthon useful in the method of the invention.

摘要翻译： 本发明提供了一种获得18 F-标记的化合物的新方法，其中所述化合物包含18 F-标记的吡啶基环。 本发明的方法优于现有技术方法，因为它提供的这些化合物的放射化学产率比以前的方法所能达到的要高。 本发明还提供了用于本发明方法的18 F-标记的合成子。