公开(公告)号：EP2026844A2

公开(公告)日：2009-02-25

申请号：EP07732982.9

申请日：2007-05-25

申请人： GE Healthcare Limited ,  GE HEALTHCARE AS

发明人： CHETTIBI, Salah ,  NEWTON, Ben ,  HUSBYN, Mette ,  SOLBAKKEN, Magne ,  BROWN, Jane GE Healthcare Limited ,  BHALLA, Rhajiv GE Healthcare Limited ,  IVESON, Peter GE Healthcare Limited ,  KRAMER, Daniel

IPC分类号： A61K49/00 ,  A61K51/00

CPC分类号： A61K51/088 ,  A61K49/0002

摘要： The present invention provides a novel imaging agent suitable for the non-invasive visualization of fibrosis. A precursor for the preparation of the imaging agent is also provided by the invention, as well as a pharmaceutical composition comprising the imaging agent and a kit for the preparation of the pharmaceutical composition. In a further aspect, use of the imaging agent for in vivo imaging and in the preparation of a medicament for the diagnosis of a condition which comprises fibrosis is provided.

公开(公告)号：EP2121542A1

公开(公告)日：2009-11-25

申请号：EP08718631.8

申请日：2008-03-07

申请人： GE Healthcare Limited

发明人： HUSBYN, Mette

IPC分类号： C07B59/00

CPC分类号： C07B59/005

摘要： The present invention relates to a process for separating a target radiolabelled compound from an impurity, apparatus for performing such a process and a removable cassette for use in such apparatus. Also provided are methods for using the target radiolabelled compound obtained by a method comprising the separating process of the invention.