公开(公告)号：EP2100142B1

公开(公告)日：2012-02-08

申请号：EP07865144.5

申请日：2007-12-04

申请人： General Electric Company

发明人： NELSON, John R. ,  MOASSER, Bahram ,  SOOD, Anup ,  GROSSMANN, Gregory A. ,  LV, Su ,  PAN, Zhida ,  QIANG, Liangliang ,  GUI, John Yupeng ,  CAI, Wei ,  ZHENG, Zhixin

IPC分类号： G01N33/532 ,  G01N33/533 ,  G01N33/58 ,  G01N33/542

CPC分类号： G01N33/5308

摘要： A composition includes a first probe, a first initiator component bonded to the first probe, a second probe, and a second initiator component bonded to the second probe. The first probe and the second probe are capable of binding to a single analyte, and the first initiator component and the second initiator component are capable of forming an initiator when present in proximity to each other and when the first probe and the second probe are bonded to the analyte. An associated kit, device, and method are provided.

公开(公告)号：EP2106452A2

公开(公告)日：2009-10-07

申请号：EP08705788.1

申请日：2008-01-09

申请人： GENERAL ELECTRIC COMPANY

发明人： NELSON, John R. ,  DUTHIE, Robert Scott ,  FULLER, Carl Williams ,  GROSSMANN, Gregory A. ,  SEKHER, Anuradha

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6858 ,  C12Q1/6844 ,  C12Q2527/101 ,  C12Q2525/101 ,  C12Q2521/301

摘要： Provided herein are nucleic acid synthesis methods and agents that employ an endonuclease for example, endonuclease V, to introduce a nick into a target DNA including one or more inosine, and uses a DNA polymerase to generate amplicons of the target DNA.

摘要翻译： 本文提供了核酸合成方法和试剂，其使用内切核酸酶例如内切核酸酶V将切口引入包含一个或多个肌苷的靶DNA中，并使用DNA聚合酶来产生靶DNA的扩增子。

公开(公告)号：EP2100142A1

公开(公告)日：2009-09-16

申请号：EP07865144.5

申请日：2007-12-04

申请人： GENERAL ELECTRIC COMPANY

发明人： NELSON, John R. ,  MOASSER, Bahram ,  SOOD, Anup ,  GROSSMANN, Gregory A. ,  LV, Su ,  PAN, Zhida ,  QIANG, Liangliang ,  GUI, John Yupeng ,  CAI, Wei ,  ZHENG, Zhixin

IPC分类号： G01N33/532 ,  G01N33/533 ,  G01N33/58 ,  G01N33/542

CPC分类号： G01N33/5308

摘要： A composition includes a first probe, a first initiator component bonded to the first probe, a second probe, and a second initiator component bonded to the second probe. The first probe and the second probe are capable of binding to a single analyte, and the first initiator component and the second initiator component are capable of forming an initiator when present in proximity to each other and when the first probe and the second probe are bonded to the analyte. An associated kit, device, and method are provided.