专利检索 ap:("GIST-BROCADES B.V.") AND inv:"VOLLEBREGT, Adrianus, Wilhelmus, Hermanus" 第 1 页

1.

发明公开
PROCESS FOR THE FERMENTATIVE PRODUCTION OF DEACYLATED CEPHALOSPORINS 失效
标题翻译：工艺发酵生产头孢菌素DEAZYLIERTEN的。

公开(公告)号：EP0915988A1

公开(公告)日：1999-05-19

申请号：EP98929264.0

申请日：1998-04-22

申请人： GIST-BROCADES B.V.

发明人： NIEBOER, Maarten , DE VROOM, Erik , LUGTENBURG, Johannis , SCHIPPER, Dirk , VOLLEBREGT, Adrianus, Wilhelmus, Hermanus , BOVENBERG, Roelof, Ary, Lans

IPC分类号： C12P17 , C12N1 , C12N9 , C12N15 , C12P35 , C12P37 , C12R1

CPC分类号： C12N9/0071 , C12N9/1029 , C12P35/00 , C12P37/04 , Y10S435/935

摘要： The present invention discloses a process for the production of N-deacylated cephalosporin compounds via the fermentative production of their 7-acylated counterparts.

2.

发明公开
PROCESS FOR THE PRODUCTION OF 7-ADCA VIA EXPANDASE ACTIVITY ON PENICILLIN G 失效
标题翻译：过程对于7-ADCA BY实施青霉素G的制备机构扩

公开(公告)号：EP0828850A1

公开(公告)日：1998-03-18

申请号：EP96917498.0

申请日：1996-06-03

申请人： GIST-BROCADES B.V.

发明人： BOVENBERG, Roelof, Ary, Lans , KOEKMAN, Bertus, Pieter , SCHIPPER, Dirk , VOLLEBREGT, Adrianus, Wilhelmus, Hermanus

IPC分类号： C12N9 , C12P35

CPC分类号： C12N9/0071 , C12P35/00

摘要： An overall process for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via enzymatic ring expansion activity on penicillin G, using a Penicillium chrysogenum transformant strain expressing expandase.