公开(公告)号：EP4117648A1

公开(公告)日：2023-01-18

申请号：EP21768391.1

申请日：2021-03-10

申请人： GNT Pharma Co., Ltd

发明人： GWAG, Byoung Joo ,  AN, Chun San ,  JIN, Jing Yu ,  CHO, Sung Ig ,  ZHU, Fangmeng ,  XU, Xinliang ,  ZHAN, Weiqiang ,  LIU, Fuxin ,  WON, Soon-Mi

IPC分类号： A61K31/196 ,  A61K45/06 ,  A61P9/10 ,  A61P25/00 ,  C07C229/64

公开(公告)号：EP4190314A1

公开(公告)日：2023-06-07

申请号：EP21848554.8

申请日：2021-07-27

申请人： GNT Pharma Co., Ltd

发明人： ZHAN, Weiqiang ,  WANG, Zhanguo ,  ZHANG, Wei ,  FU, Lingyan ,  LIN, Qian ,  CHEN, Xiaoli ,  LV, Guoyang ,  ZHONG, Liyin ,  XU, Xinliang ,  ZHU, Fangmeng

IPC分类号： A61K9/19 ,  A61K31/196 ,  A61P25/00 ,  A61P9/10

摘要： A salfaprodil freeze-dried powder injection, and a preparation method thereof and the use thereof. The preparation method used in the present invention comprises the following steps: adding salfaprodil into water for injection, filtering after the salfaprodil is completely dissolved, adjusting pH of filtrate with an alkaline substance water solution, adding the injection water to achieve a constant volume, filling with an inert gas for protection, and performing sterilization and filtration to obtain a salfaprodil solution, which is then freeze-dried to obtain the salfaprodil freeze-dried powder injection.