公开(公告)号：EP1504107A1

公开(公告)日：2005-02-09

申请号：EP03722604.0

申请日：2003-05-13

申请人： GSF-Forschungszentrum für Umwelt und Gesundheit GmbH

发明人： BAIER, Robert ,  BOULANGER, DeniseCancer Research UK Oncology Unit ,  ERLFE, Volker ,  SUTTER, Gerd

IPC分类号： C12N15/86 ,  C07K14/065 ,  A61K35/76 ,  A61K39/00 ,  C12N5/10

CPC分类号： A61K39/0011 ,  A61K48/00 ,  A61K2039/5256 ,  A61K2039/53 ,  A61K2039/545 ,  C12N15/86 ,  C12N2710/24043 ,  C12N2710/24143

摘要： The invention relates to a recombinant fowlpox virus (FWPV) and a DNA vector containing gene sequences for one such recombinant fowlpox virus. The invention also relates to a pharmaceutical composition containing said recombinant fowlpox virus or a DNA vector, to the use of said recombinant fowlpox virus for treating infectious diseases or tumour diseases, and to a method for producing said recombinant fowlpox virus or DNA vector. The invention further relates to eukaryote cells or prokaryote cells containing the recombinant DNA vector or the recombinant fowlpox virus. The invention is based on the identification of the FWPV-F11L gene as a novel insertion site for foreign DNA.