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1.发明公开TRIAZOLOPYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES 有权TRIAZOLOPYRAZINVERBINDUNGEN用于治疗退化性疾病和炎性疾病
公开(公告)号：EP2029602A2
公开(公告)日：2009-03-04
申请号：EP07729660.6
申请日：2007-05-30
申请人： Galapagos N.V.
发明人： ANDREWS, Martin James Inglis , EDWARDS, Paul , CHAMBERS, Mark Stuart , SCHMIDT, Wolfgang , CLASE, Juha Andrew , BAR, Gregory , HIRST, Kim Louise , MACLEOD, Angus
IPC分类号： C07D487/04 , A61K31/4985 , A61P29/00
CPC分类号： C07D487/04
摘要： Novel [1.2.4]triazolo[1,5-a]pyrazine compounds are disclosed that have a formula represented by the following (formula I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, arthritis, inflammation, and others.
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2.发明授权TRIAZOLOPYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES 有权TRIAZOLOPYRAZINVERBINDUNGEN用于治疗退化性疾病和炎性疾病
公开(公告)号：EP2029602B1
公开(公告)日：2010-04-21
申请号：EP07729660.6
申请日：2007-05-30
申请人： Galapagos N.V.
发明人： ANDREWS, Martin James Inglis , EDWARDS, Paul , CHAMBERS, Mark Stuart , SCHMIDT, Wolfgang , CLASE, Juha Andrew , BAR, Gregory , HIRST, Kim Louise , MACLEOD, Angus
IPC分类号： C07D487/04 , A61K31/4985 , A61P29/00
CPC分类号： C07D487/04
摘要： Novel [1.2.4]triazolo[1,5-a]pyrazine compounds are disclosed that have a formula represented by the following (formula I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, arthritis, inflammation, and others.
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3.发明公开IMIDAZOLOPYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES 有权IMIDAZOLPYRAZINVERBINDUNGEN用于治疗退化性疾病和炎性疾病
公开(公告)号：EP2027124A1
公开(公告)日：2009-02-25
申请号：EP07729106.0
申请日：2007-05-14
申请人： Galapagos N.V.
发明人： BRYS, Reginald Christophe Xavier , EDWARDS, Paul , SCHMIDT, Wolfgang , ANDREWS, Martin James Inglis , CHAMBERS, Mark Stuart , CLASE, Juha Andrew , BIRAULT, Veronique , HIRST, Kim Louise , MACLEOD, Angus , BAR, Gregory , HARRIS, Clifford John , HUXLEY, Philip
IPC分类号： C07D487/04 , A61K31/4985 , A61P19/02
CPC分类号： C07D487/04
摘要： Novel imidazo[1,2-a]pyrazine compounds are disclosed that have a formula ( I ) represented by the following:The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, arthritis, inflammation, and others.
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