公开(公告)号：EP1546182B1

公开(公告)日：2011-01-05

申请号：EP03752035.0

申请日：2003-09-05

申请人： Genentech, Inc.

发明人： DAVIS, David P. ,  DeSAUVAGE, Frederic J. ,  WOOD, William I. ,  ZHANG, Zemin

IPC分类号： C07K1/00 ,  C07H21/04 ,  C12P21/06 ,  C12N5/00 ,  A61K39/00 ,  A61K39/395 ,  A01N61/00

CPC分类号： C12N9/12 ,  A61K38/00 ,  C12N9/1205 ,  C12N2310/14

摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

公开(公告)号：EP2097530A1

公开(公告)日：2009-09-09

申请号：EP07865189.0

申请日：2007-12-04

申请人： Genentech, Inc.

发明人： DAVIS, David P. ,  GRAY, Daniel C. ,  GU, Zhenyu

IPC分类号： C12N15/63 ,  C12N15/11

CPC分类号： C12N15/635 ,  C12N15/111 ,  C12N15/1135 ,  C12N15/1136 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2320/50 ,  C12N2330/30

摘要： Compositions and methods are provided herein for the expression of nucleic acids. Compositions and methods are also provided herein for inducible expression of nucleic acids in transgenic cells and animals using transposon-based nucleic acid constructs. Compositions and methods are also provided herein for modulation of endogenous gene expression.

公开(公告)号：EP1546182A2

公开(公告)日：2005-06-29

申请号：EP03752035.0

申请日：2003-09-05

申请人： Genentech, Inc.

发明人： DAVIS, David P. ,  DeSAUVAGE, Frederic J. ,  WOOD, William I. ,  ZHANG, Zemin

IPC分类号： C07K1/00 ,  C07H21/04 ,  C12P21/06 ,  C12N5/00 ,  A61K39/00 ,  A61K39/395 ,  A01N61/00

CPC分类号： C12N9/12 ,  A61K38/00 ,  C12N9/1205 ,  C12N2310/14

摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.