专利检索 ap:("Genentech, Inc." OR "Constellation Pharmaceuticals, Inc.") AND inv:"LORA, Jose M." 第 1 页

1.

发明公开
TREATING TH2-MEDIATED DISEASES BY INHIBITION OF BROMODOMAIN-COMPRISING PROTEINS BRD7 AND BRD9 审中-公开
标题翻译：治疗TH2诱发的疾病，通过抑制BROMDOMÄNEN蛋白和BRD7 BRD9

公开(公告)号：EP2968263A2

公开(公告)日：2016-01-20

申请号：EP14729995.2

申请日：2014-03-14

申请人： Genentech, Inc. , Constellation Pharmaceuticals, Inc.

发明人： ALBRECHT, Brian K. , COTE, Alexandre , CRAWFORD, Terry , FAUBER, Benjamin , HUANG, Hon-Ren , LORA, Jose M. , MAGNUSON, Steven , NASVESCHUK, Christopher G. , SALMERON, Andres , SIMS III, Robert J. , TAYLOR, Alexander M.

IPC分类号： A61K31/395 , A61K31/7105 , C07D471/04 , C12N15/113 , G01N33/50 , G01N33/68

CPC分类号： C12N15/113 , A61K31/437 , A61K31/444 , A61K31/496 , A61K31/713 , C07K14/4702 , C12N2310/14 , C12N2320/30 , G01N33/505 , G01N2333/52 , G01N2500/04 , G01N2500/10 , Y02A50/422

摘要： The invention provides methods for treating Th2 cytokine-mediated diseases by inhibiting bromodomain function.

摘要翻译： 本发明提供了通过抑制溴基结构域的功能治疗Th2细胞因子介导的疾病的方法。