公开(公告)号：EP3356360A1

公开(公告)日：2018-08-08

申请号：EP16781926.7

申请日：2016-09-27

申请人： Genentech, Inc. ,  Xenon Pharmaceuticals Inc.

发明人： BERGERON, Phillipe ,  BURFORD, Kristen ,  CHOWDHURY, Sultan ,  DEHNHARDT, Christoph Martin ,  FOCKEN, Thilo ,  GRIMWOOD, Michael Edward ,  HASAN, Abid ,  LAI, Kwong Wah ,  LIU, Zhiguo ,  MCKERRALL, Steven ,  NGUYEN, Teresa Phuongtram ,  SAFINA, Brian ,  SUTHERLIN, Daniel ,  WANG, Tao

IPC分类号： C07D417/12 ,  C07D417/14 ,  A61K31/445 ,  A61P29/00

CPC分类号： C07D417/12 ,  A61P17/04 ,  C07D401/12 ,  C07D405/14 ,  C07D417/14 ,  C07D491/107

摘要： or a salt thereof, wherein the variables RAA, n, ring A, ring B, R1a, R1b, R2, R3, R4, R5, R6, R7, R8, and R9 have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.