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1.发明公开
公开(公告)号：EP2726443A1
公开(公告)日：2014-05-07
申请号：EP12738666.2
申请日：2012-06-28
发明人： RENSCH, Christian , BALLER, Marko , BOELD, Christoph , HORVATH-KLEIN, Ruben Julian , SAMPER, Victor , ULIN, Johan
摘要： Disclosed are devices and methods for reducing radiolysis of radiopharmaceuticals during filtration, concentration and purification. The devices comprises two or more confining geometry having a cross-section dimension below the beta(+) or beta(-) range of the radioisotope in use, when containing the radioisotope, and configured in such a way that neighboring geometries are isolated from its nearest neighbor such that no measurable kinetic positron energy transfer occurs between the confining geometries when containing the radioisotope. Methods of filtration of radioisotope containing mixtures are also disclosed.
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公开(公告)号：EP2797683A1
公开(公告)日：2014-11-05
申请号：EP12818722.6
申请日：2012-12-19
CPC分类号： B01J19/0093 , B01J2219/0081 , B01J2219/00986 , G01N35/00029 , G01N35/04 , G01N2035/0425
摘要： Techniques and devices are provided related to a handling system for cassettes for radiolabeled compound synthesis that include a magazine that is unshielded and that is configured to receive a plurality of microfluidic synthesis cassettes. In one embodiment, the plurality of microfluidic synthesis cassettes include nonradioactive reagents to generate a radiolabeled compound when reacted with a radioactive isotope. In this manner, a cassette handling device may be stored unshielded and may be coupled to a cassette handling platform to allow advancement of the plurality of microfluidic synthesis cassettes into the cassette handling platform and, in turn, a shielded radiosynthesis machine.
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