专利检索 ap:("Genfleet Therapeutics (Shanghai) Inc." OR "Zhejiang Genfleet Therapeutics Co., Ltd.") AND inv:"CAO, Yudong" 第 1 页

1.

发明公开
POLYMORPH OF KRAS INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 审中-公开

公开(公告)号：EP4455147A1

公开(公告)日：2024-10-30

申请号：EP22910205.8

申请日：2022-12-23

申请人： Genfleet Therapeutics (Shanghai) Inc. , Zhejiang Genfleet Therapeutics Co., Ltd.

发明人： ZHOU, Fusheng , ZHAO, Jinzhu , CAO, Yudong , XIONG, Lun , SHI, Rongzhen , LAN, Jiong

IPC分类号： C07D487/22 , A61K31/4985 , A61P35/00

摘要： Provided are a polymorph of a KRAS inhibitor, a preparation method therefor, and a use thereof. Specifically disclosed is a pharmaceutically acceptable salt of a compound 1 or a polymorph of the compound or pharmaceutically acceptable salt thereof, and further disclosed are a preparation method for the salt or polymorph and an application of the salt or polymorph in the treatment and/or prevention of KRAS G12C mutation-related diseases.