公开(公告)号：EP2376537B1

公开(公告)日：2016-09-28

申请号：EP09801426.9

申请日：2009-12-09

申请人： Genmab A/S

发明人： VERPLOEGEN, Sandra ,  SATIJN, David, P., E. ,  HOET, Rene, M., A ,  PARREN, Paul ,  VAN DE WINKEL, Jan ,  BREINHOLT, Vibeke, Miller ,  EHRNROOTH, Eva ,  BAADSGAARD, Ole ,  VINK, Tom ,  BLEEKER, Willem, Karel ,  HOUTKAMP, Mischa ,  OUDSHOORN, Maroeska ,  DE JONG, Rob, N.

IPC分类号： C07K16/36 ,  A61P35/00 ,  A61K39/395

CPC分类号： C07K16/36 ,  A61K39/395 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/31 ,  C07K2317/565 ,  C07K2317/732 ,  C07K2317/76 ,  C07K2317/92

摘要： Isolated human monoclonal antibodies which bind to human TF and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.

公开(公告)号：EP2376537A2

公开(公告)日：2011-10-19

申请号：EP09801426.9

申请日：2009-12-09

申请人： Genmab A/S

发明人： VERPLOEGEN, Sandra ,  SATIJN, David, P., E. ,  HOET, Rene, M., A ,  PARREN, Paul ,  VAN DE WINKEL, Jan ,  BREINHOLT, Vibeke, Miller ,  EHRNROOTH, Eva ,  BAADSGAARD, Ole ,  VINK, Tom ,  BLEEKER, Willem, Karel ,  HOUTKAMP, Mischa ,  OUDSHOORN, Maroeska ,  DE JONG, Rob, N.

IPC分类号： C07K16/36 ,  A61P35/00

CPC分类号： C07K16/36 ,  A61K39/395 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/31 ,  C07K2317/565 ,  C07K2317/732 ,  C07K2317/76 ,  C07K2317/92

摘要： Isolated human monoclonal antibodies which bind to human TF and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.