公开(公告)号：EP3212629A1

公开(公告)日：2017-09-06

申请号：EP15837091.6

申请日：2015-10-26

申请人： Genoscience Pharma SAS

发明人： BASSISSI, Firas ,  BERET, Antoine ,  BRUN, Sonia ,  COURCAMBECK, Jérôme ,  DUBRAY, Clarisse ,  NICOLAS, Gregory ,  HALFON, Philippe

IPC分类号： C07D401/04 ,  A61K31/47 ,  A61P35/00

CPC分类号： C07D401/04

摘要： The present invention relates to novel 2-primary amino-4-secondary amino-quinoline derivatives, their manufacture, pharmaceutical compositions comprising them and their use as medicaments. The active compounds of the present invention are useful for the treatment and prevention of proliferative neoplastic and non-neoplastic diseases.

摘要翻译： 本发明涉及新颖的2-伯氨基-4-仲氨基喹啉衍生物，它们的制造方法，包含它们的药物组合物以及它们作为药物的用途。 本发明的活性化合物可用于治疗和预防增生性赘生性和非赘生性疾病。

公开(公告)号：EP3212629B1

公开(公告)日：2018-10-24

申请号：EP15837091.6

申请日：2015-10-26

申请人： Genoscience Pharma SAS

发明人： BASSISSI, Firas ,  BERET, Antoine ,  BRUN, Sonia ,  COURCAMBECK, Jérôme ,  DUBRAY, Clarisse ,  NICOLAS, Gregory ,  HALFON, Philippe

IPC分类号： C07D401/04 ,  A61K31/47 ,  A61P35/00

CPC分类号： C07D401/04

摘要： The present invention relates to novel 2-primary amino-4-secondary amino-quinoline derivatives, their manufacture, pharmaceutical compositions comprising them and their use as medicaments. The active compounds of the present invention are useful for the treatment and prevention of proliferative neoplastic and non-neoplastic diseases.

公开(公告)号：EP2976333B1

公开(公告)日：2018-08-08

申请号：EP14770929.9

申请日：2014-03-13

申请人： Genoscience Pharma SAS

发明人： COURCAMBECK, Jerome ,  BASSISSI, Firas ,  BRUN, Sonia ,  NICOLAS, Gregory ,  BERET, Antoine ,  PETIT, Serge ,  CAMUS, Claire ,  NALLET, Jean Pierre ,  HALFON, Philippe

IPC分类号： C07D401/04 ,  C07D401/14 ,  C07D215/46 ,  C07D413/14 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/5377 ,  A61P35/00

CPC分类号： C07D215/52 ,  A61K31/47 ,  A61K31/4706 ,  A61K31/4709 ,  A61K31/5377 ,  A61K45/06 ,  C07D211/58 ,  C07D211/74 ,  C07D215/12 ,  C07D215/18 ,  C07D215/233 ,  C07D215/42 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D491/113

摘要： The invention provides quinoline derivatives, their manufacture, pharmaceutical compositions containing them, and their use as medicaments. The active compounds of the present invention are useful for the treatment of proliferative neoplastic and non-neoplastic diseases.

公开(公告)号：EP2976333A1

公开(公告)日：2016-01-27

申请号：EP14770929.9

申请日：2014-03-13

申请人： Genoscience Pharma SAS

发明人： COURCAMBECK, Jerome ,  BASSISSI, Firas ,  BRUN, Sonia ,  NICOLAS, Gregory ,  BERET, Antoine ,  PETIT, Serge ,  CAMUS, Claire ,  NALLET, Jean Pierre ,  HALFON, Philippe

IPC分类号： C07D401/04 ,  C07D401/14 ,  C07D215/46 ,  C07D413/14 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/5377 ,  A61P35/00

CPC分类号： C07D215/52 ,  A61K31/47 ,  A61K31/4706 ,  A61K31/4709 ,  A61K31/5377 ,  A61K45/06 ,  C07D211/58 ,  C07D211/74 ,  C07D215/12 ,  C07D215/18 ,  C07D215/233 ,  C07D215/42 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D491/113

摘要： The invention provides quinoline derivatives, their manufacture, pharmaceutical compositions containing them, and their use as medicaments. The active compounds of the present invention are useful for the treatment of proliferative neoplastic and nonneoplastic diseases.