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公开(公告)号：EP2612680A1
公开(公告)日：2013-07-10
申请号：EP13162452.0
申请日：2009-04-16
IPC分类号： A61K39/09 , A61K39/102 , A61K39/145 , A61K39/295 , A61K39/39
CPC分类号： A61K39/092 , A61K39/102 , A61K39/12 , A61K39/145 , A61K2039/5252 , A61K2039/545 , A61K2039/55566 , A61K2039/70 , C12N2760/16134 , C12N2760/16234
摘要： The present invention provides an immunogenic composition comprising a Streptococcus pneumoniae antigen and an adjuvant composition comprising an oil in water emulsion, wherein said oil in water emulsion comprises 0.5 - 10 mg metabolisable oil, 0.5 - 11 mg tocol and 0.1 - 4 mg emulsifying agent, per human dose.
摘要翻译： 本发明提供了包含肺炎链球菌抗原和包含水包油乳剂的佐剂组合物的免疫原性组合物，其中所述水包油乳剂包含0.5-10mg可代谢油，0.5-11mg母育酚和0.1-4mg乳化剂， 每人剂量。
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公开(公告)号：EP2281830A3
公开(公告)日：2012-01-25
申请号：EP10188214.0
申请日：2006-03-01
CPC分类号： A61K39/25 , A61K39/00 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C12N2710/16722 , C12N2710/16734
摘要： Use of an immunogenic composition comprising VZV gE, or immunogenic fragment thereof, and a TH-1 adjuvant in the preparation of a medicament for the prevention or amelioration of shingles and/or post herpetic neuralgia. Compositions comprising a truncated VZV gE antigen and an adjuvant containing QS21, cholesterol and 3D MPL arc also claimed.
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公开(公告)号：EP2612680B1
公开(公告)日：2018-05-23
申请号：EP13162452.0
申请日：2009-04-16
IPC分类号： A61K39/00 , A61K39/09 , A61K39/12 , A61K39/39 , A61K39/102 , A61K39/145 , A61K39/295
CPC分类号： A61K39/092 , A61K39/102 , A61K39/12 , A61K39/145 , A61K2039/5252 , A61K2039/545 , A61K2039/55566 , A61K2039/70 , C12N2760/16134 , C12N2760/16234
摘要： The present invention provides an immunogenic composition comprising a Streptococcus pneumoniae antigen and an adjuvant composition comprising an oil in water emulsion, wherein said oil in water emulsion comprises 0.5 - 10 mg metabolisable oil, 0.5 - 11 mg tocol and 0.1 - 4 mg emulsifying agent, per human dose.
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公开(公告)号：EP2301955B1
公开(公告)日：2018-04-18
申请号：EP10188215.7
申请日：2006-03-01
CPC分类号： A61K39/25 , A61K39/00 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C12N2710/16722 , C12N2710/16734
摘要： Use of an immunogenic composition comprising VZV gE, or immunogenic fragment thereof, and a TH-1 adjuvant in the preparation of a medicament for the prevention or amelioration of shingles and/or post herpetic neuralgia. Compositions comprising a truncated VZV gE antigen and an adjuvant containing QS21, cholesterol and 3D MPL arc also claimed.
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公开(公告)号：EP2281830B1
公开(公告)日：2016-12-21
申请号：EP10188214.0
申请日：2006-03-01
CPC分类号： A61K39/25 , A61K39/00 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C12N2710/16722 , C12N2710/16734
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公开(公告)号：EP2301955A3
公开(公告)日：2011-11-16
申请号：EP10188215.7
申请日：2006-03-01
CPC分类号： A61K39/25 , A61K39/00 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C12N2710/16722 , C12N2710/16734
摘要： Use of an immunogenic composition comprising VZV gE, or immunogenic fragment thereof, and a TH-1 adjuvant in the preparation of a medicament for the prevention or amelioration of shingles and/or post herpetic neuralgia. Compositions comprising a truncated VZV gE antigen and an adjuvant containing QS21, cholesterol and 3D MPL arc also claimed.
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公开(公告)号：EP2301955A2
公开(公告)日：2011-03-30
申请号：EP10188215.7
申请日：2006-03-01
CPC分类号： A61K39/25 , A61K39/00 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C12N2710/16722 , C12N2710/16734
摘要： Use of an immunogenic composition comprising VZV gE, or immunogenic fragment thereof, and a TH-1 adjuvant in the preparation of a medicament for the prevention or amelioration of shingles and/or post herpetic neuralgia. Compositions comprising a truncated VZV gE antigen and an adjuvant containing QS21, cholesterol and 3D MPL arc also claimed.
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公开(公告)号：EP2281830A2
公开(公告)日：2011-02-09
申请号：EP10188214.0
申请日：2006-03-01
CPC分类号： A61K39/25 , A61K39/00 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C12N2710/16722 , C12N2710/16734
摘要： Use of an immunogenic composition comprising VZV gE, or immunogenic fragment thereof, and a TH-1 adjuvant in the preparation of a medicament for the prevention or amelioration of shingles and/or post herpetic neuralgia. Compositions comprising a truncated VZV gE antigen and an adjuvant containing QS21, cholesterol and 3D MPL arc also claimed.
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