公开(公告)号：EP3880182A1

公开(公告)日：2021-09-22

申请号：EP19885548.8

申请日：2019-11-15

申请人： Graybug Vision, Inc.

发明人： YANG, Ming ,  SALAIN, Daniel, Louis ,  SEMBA, Charles, Pauling ,  YU, Yun ,  YU, Weiling ,  KAYS, Joshua ,  CHISHOLM, Jane ,  LU, Qingyun ,  CLELAND, Jeffrey, L.

IPC分类号： A61K9/16 ,  A61K9/00 ,  A61K47/00

公开(公告)号：EP3373978A1

公开(公告)日：2018-09-19

申请号：EP16865170.1

申请日：2016-11-11

申请人： Graybug Vision, Inc.

发明人： YU, Yun ,  KAYS, Joshua ,  YANG, Ming ,  CLELAND, Jeffrey, L.

IPC分类号： A61K47/50 ,  A61K9/14 ,  A61K9/50

CPC分类号： A61K9/5089 ,  A61K9/0019 ,  A61K9/0048 ,  A61K9/1641 ,  A61K9/1647 ,  A61K9/5026 ,  A61K9/5031 ,  A61K31/404 ,  A61K47/10 ,  A61K47/26 ,  A61K47/36

摘要： The present invention is a surface treated drug-loaded solid (e.g., non-porous) microparticle that aggregates in vivo to form a consolidated larger particle for medical therapy. In one embodiment, the particles are used for ocular therapy. Processes for producing the surface treated microparticle and injectable formulations which include the surface treated microparticle are also provided. When used in the eye, long-term consistent intraocular delivery can be achieved without disrupting vision and minimizing undesirable inflammatory responses.

公开(公告)号：EP3621654A1

公开(公告)日：2020-03-18

申请号：EP18797994.3

申请日：2018-05-10

申请人： Graybug Vision, Inc.

发明人： YANG, Ming ,  CLELAND, Jeffrey, L. ,  YU, Yun ,  YU, Weiling ,  KAYS, Joshua

IPC分类号： A61K47/10 ,  A61K47/36 ,  A61K9/50