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1.发明公开
公开(公告)号：EP3699199A2
公开(公告)日：2020-08-26
申请号：EP18868854.3
申请日：2018-10-22
发明人： KIM, Ki Su , JEONG, Jun Hong , KIM, Dong Sik , LIM, Yang Mi , PARK, Yong Yea , LIM, Hyung Kwon , WON, Jong Wha
IPC分类号： C07K16/30
摘要： The present invention relates to an anti-MSLN antibody and a pharmaceutical composition for cancer treatment comprising same. The anti-MSLN antibody according to the present invention has high affinity and specificity for MSLN and thus can be effectively used in cancer prevention or treatment.
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公开(公告)号：EP3699192A2
公开(公告)日：2020-08-26
申请号：EP18867685.2
申请日：2018-10-22
发明人： KIM, Ki Su , JEONG, Jun Hong , YOON, Ae Rin , SONG, Eun Jung , CHOI, Hye Ji , LIM, Ok Jae , LEE, Yun Jung , LIM, Hyung-Kwon , WON, JongWha
IPC分类号： C07K16/28
摘要： The present invention relates to an anti-CD3 antibody and a pharmaceutical composition for cancer treatment comprising same. The antibody according to the present invention has high affinity and specificity for CD3 and thus can be effectively used in cancer prevention or treatment.
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公开(公告)号：EP3875483A1
公开(公告)日：2021-09-08
申请号：EP19877066.1
申请日：2019-10-18
发明人： CHO, Ki Joon , LEE, Mijung , SONG, Eun Jung , KIM, Ki Su , KANG, Kwan Yub , CHO, Eui Cheol
摘要： The present invention relates to an asymmetric fusion protein in which a fragment of an antibody binding to an insulin receptor, an IDS enzyme, and an Fc region are fused, and a use thereof. The fusion protein can cross the blood-brain barrier (BBB) to deliver the IDS enzyme to the brain. Therefore, a pharmaceutical composition comprising the fusion protein as an active ingredient can be used as a therapeutic agent for a central nervous system disease and particularly, is expected to prevent and treat various diseases caused by ribosome accumulation.
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