公开(公告)号：EP4241843A2

公开(公告)日：2023-09-13

申请号：EP23176632.0

申请日：2018-02-20

申请人： H. Lundbeck A/S

发明人： ROTTLÄNDER, Mario ,  SAMS, Anette, Graven ,  WANG, Xiaofang ,  DAS, Debasis ,  HONG, Jian ,  CHEN, Shu Hui

IPC分类号： A61P25/28

摘要： The present invention provides novel compounds which activate the Kv7 potassium channels. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders responsive to the activation of Kv7 potassium channels.

公开(公告)号：EP4461725A2

公开(公告)日：2024-11-13

申请号：EP24203380.1

申请日：2020-07-30

申请人： H. Lundbeck A/S

发明人： SAMS, Anette, Graven ,  ROTTLÄNDER, Mario ,  LARSEN, Krestian ,  WANG, Xiaofang ,  DAS, Debasis ,  HONG, Jian ,  CHEN, Shu, Hui

IPC分类号： C07C235/08

摘要： The present invention provides novel compounds which activate the Kv7 potassium channels. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders responsive to the activation of Kv7 potassium channels.

公开(公告)号：EP4241843A3

公开(公告)日：2023-09-27

申请号：EP23176632.0

申请日：2018-02-20

申请人： H. Lundbeck A/S

发明人： ROTTLÄNDER, Mario ,  SAMS, Anette, Graven ,  WANG, Xiaofang ,  DAS, Debasis ,  HONG, Jian ,  CHEN, Shu Hui

IPC分类号： C07C235/06 ,  C07C235/08 ,  A61P25/24 ,  C07C235/40 ,  A61P25/14 ,  A61P25/22 ,  A61P25/28 ,  A61P25/18 ,  A61K31/165

摘要： The present invention provides novel compounds which activate the Kv7 potassium channels. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders responsive to the activation of Kv7 potassium channels.

公开(公告)号：EP4007634A1

公开(公告)日：2022-06-08

申请号：EP20749879.1

申请日：2020-07-30

申请人： H. Lundbeck A/S

发明人： SAMS, Anette, Graven ,  ROTTLÄNDER, Mario ,  LARSEN, Krestian ,  WANG, Xiaofang ,  DAS, Debasis ,  HONG, Jian ,  CHEN, Shu, Hui

IPC分类号： A61P25/18 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  C07C235/08

公开(公告)号：EP4007571A1

公开(公告)日：2022-06-08

申请号：EP20749878.3

申请日：2020-07-30

申请人： H. Lundbeck A/S

发明人： SAMS, Anette, Graven ,  ROTTLÄNDER, Mario ,  WANG, Xiaofang ,  DAS, Debasis ,  HONG, Jian ,  CHEN, Shu, Hui ,  BASTLUND, Jesper, Frank ,  IVKOVIC, Jelena ,  SØBY, Karina, Krøjer ,  LARSEN, Morten, Grupe

IPC分类号： A61K31/165 ,  A61P25/08