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1.发明公开METHOD OF PREPARING THIENO [3,2-C]PYRIDINE DERIVATIVES AND INTERMEDIATES USED THEREIN 审中-公开PROCESS FOR PRODUCING噻吩并[3,2-C]吡啶和ENSURE USED中间产品
公开(公告)号：EP1723149A4
公开(公告)日：2009-11-18
申请号：EP05721898
申请日：2005-03-03
发明人： YUN SANGMIN , KIM EUN SOOK , KIM HEE SEOCK , HA TAE HEE , SUH KWEE-HYUN , LEE GWAN SUN
IPC分类号： C07D495/04 , C07D333/12 , C07D333/16 , C07D333/18 , C07D333/38
CPC分类号： C07D333/38 , C07D333/12 , C07D333/16 , C07D333/18 , C07D495/04
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2.发明公开
公开(公告)号：EP2121596A4
公开(公告)日：2010-03-17
申请号：EP08704884
申请日：2008-01-21
发明人： KIM EUN SOOK , JANG SUN YOUNG , KWON BO SUNG , YUN SANGMIN , SUH KWEE HYUN , LEE GWAN SUN
IPC分类号： C07D207/416 , A61K31/40 , A61P3/06
CPC分类号： C07D207/416
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公开(公告)号：EP1907397A4
公开(公告)日：2009-05-27
申请号：EP05818892
申请日：2005-11-28
发明人： KIM EUN SOOK , KIM HEE CHEOL , KWON BO SUNG , YUN SANGMIN , KO MI YOUNG , KIM CHEOL KYUNG , SUH KWEE HYUN
IPC分类号： C07D495/04
CPC分类号： C07D495/04
摘要： Optically pure clopidogrel can be prepared in a high yield by optically resolving a racemic form of the compound of formula (II) using an optically active amine to form the optically active form of the compound of formula (III) or its acid-addition salt; and methylating the compound of formula (III) or its acid-addition salt.
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4.发明公开CRYSTALLINE AZITHROMYCIN L-MALATE MONOHYDRATE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 有权结晶阿奇霉素L-苹果酸一水合物及其含有的药物组合物
公开(公告)号：EP1910392A4
公开(公告)日：2008-10-29
申请号：EP06747495
申请日：2006-06-05
发明人： KWON BO SUNG , KIM EUN SOOK , KIM HEE CHEOL , YUN SANGMIN , KO MYOUNG-SIL , SONG TAE HUN , KIM HAN KYONG , SUH KWEE HYUN , LEE GWANSUN
IPC分类号： C07H17/08
CPC分类号： C07H17/08
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5.发明公开CRYSTALLINE CLOPIDOGREL NAPHTHALENESULFONATE OR HYDRATE THEREOF, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 有权CRYSTALLINE CLOPIDOGRELNAPHTHALINSULFONAT或水合物，METHOD FOR ITS药物组合物，这包括
公开(公告)号：EP1732932A4
公开(公告)日：2010-04-21
申请号：EP04793523
申请日：2004-10-18
发明人： YUN SANGMIN , KIM EUN SOOK , KIM HEE SEOCK , KWON BO SUNG , KIM CHEOL KYUNG JUGONG , KIM HAN KYONG , SUH KWEE-HYUN , LEE GWAN SUN
IPC分类号： A61K31/4365 , C07D495/04 , A61K31/4743 , A61P7/02 , C07D498/02
CPC分类号： C07D495/04
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6.发明公开METHOD FOR PREPARING CLOPIDOGREL 1,5-NAPHTHALENEDISULFONATE OR HYDRATE THEREOF 审中-公开于制备氯吡格雷1,5-萘或其水合物
公开(公告)号：EP2001889A4
公开(公告)日：2009-04-01
申请号：EP07715692
申请日：2007-03-16
发明人： SUH KWEE HYUN , YUN SANG MIN , KIM EUN SOOK , LEE GWAN SUN
IPC分类号： C07D495/04
CPC分类号： C07D495/04
摘要： The present invention relates to a method for preparing clopidogrel 1,5-naphthalenedisulfonate or a hydrate thereof, which comprises reacting a clopidogrel-acid addition salt with disodium 1,5-naphthalenedisulfonate or its hydrate in water, or a mixture of water and an organic solvent. High quality clopidogrel 1,5-naphthalenedisulfonate can be prepared by the inventive method by way of using non-corrosive disodium 1,5-naphthalenedisulfonate.
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