公开(公告)号：EP0724885B1

公开(公告)日：2002-03-13

申请号：EP94930340.8

申请日：1994-10-19

申请人： HISAMITSU PHARMACEUTICAL CO., INC.

发明人： MUKAE, Katsuya Tsukuba Laboratory of Hisamitsu ,  MIZUMACHI, Mitsuhiro Tsukuba Laboratory of ,  ITOH, Kohki Tsukuba Laboratory of Hisamitsu

IPC分类号： A61K47/10 ,  A61K9/00

CPC分类号： A61K9/0043 ,  Y10S514/946 ,  Y10S514/947

摘要： A pernasal composition comprising a pharmacologically active substance, water and an alcohol, wherein the alcohol content is 10-70 vol. % of the whole composition. This composition is highly safe and permits rapid drug absorption and prolonged retention of blood drug level. Hence this composition and a pernasal preparation containing the same permit pernasal administration of drugs which have been difficult to administer pernasally and are expected to exhibit a satisfactory drug efficacy.

公开(公告)号：EP0724885A1

公开(公告)日：1996-08-07

申请号：EP94930340.8

申请日：1994-10-19

申请人： HISAMITSU PHARMACEUTICAL CO. INC.

发明人： MUKAE, Katsuya Tsukuba Laboratory of Hisamitsu ,  MIZUMACHI, Mitshuiro Tsukuba Laboratory of ,  ITOH, Kohki Tsukuba Laboratory of Hisamitsu

IPC分类号： A61K47/10

CPC分类号： A61K9/0043 ,  Y10S514/946 ,  Y10S514/947

摘要： A pernasal composition comprising a pharmacologically active substance, water and an alcohol, wherein the alcohol content is 10-70 vol. % of the whole composition. This composition is highly safe and permits rapid drug absorption and prolonged retention of blood drug level. Hence this composition and a pernasal preparation containing the same permit pernasal administration of drugs which have been difficult to administer pernasally and are expected to exhibit a satisfactory drug efficacy.

摘要翻译： 包含药理活性物质，水和醇的鼻周组合物，其中所述醇含量为10-70体积％。 占整个组成的百分比。 这种组合物是高度安全的，可以快速吸收药物并延长血药浓度。 因此，该组合物和包含相同许可证的鼻内给药的鼻内制剂，其经口鼻管难以施用并预期具有令人满意的药效。