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公开(公告)号：EP0592664A1
公开(公告)日：1994-04-20
申请号：EP91905483.3
申请日：1991-03-07
发明人： SAITA, Masaru, 855-75, Kokura , INOUE, Hisataka, 1473-10, Tsubukuhonmachi , IKESUE, Kouichi, 193-1, Yamaryo Morodomimachi , FUJIMOTO, Noriyuki, 1175-3, Sakuramachi , SHINOHARA, Ikuo, 786-1, Tashirodaikanmachi , TANIGUCHI, Yasuaki, 567-1, Tashirohokamachi , DEGUCHI, Yoshiki, 1175-3, Sakuramachi , MINAMI, Hidenao, 1032-3, Ooazafutsukaichi , NODA, Kanji, 320-93, Ooazatsunematsu
IPC分类号： C07D277/44 , C07D277/52 , C07D277/46
CPC分类号： C07D277/46 , C07D277/52
摘要： A novel diphenylthiazole derivative which is effectively used as a medicine with an anti-inflammaory, analgesic, antiallergic, uric acid excretion stimulating, or platelet aggregation inhibiting action and is represented by general formula (I), wherein m and n are each 1 or 2; R¹ and R² each represents hydrogen, lower alkyl, lower alkoxy, lower alkylsulfonyl, nitro, amino, methanesulfonyloxy, or halogen; A¹ represents lower alkanesulfonyl, halogenated lower alkanesulfonyl, substituted bezenesulfonyl, lower acyl, or halogenated lower acyl; and A² represents hydrogen, lower alkanesulfonyl, halogenated lower alkanesulfonyl, or lower alkyl.
摘要翻译： 一种新的二苯基噻唑衍生物，其有效地用作具有抗炎，镇痛，抗过敏，尿酸排泄刺激或血小板聚集抑制作用的药物，并且由通式（I）表示，其中m和n各自为1或2 ; R 1和R 2各代表氢，低级烷基，低级烷氧基，低级烷基磺酰基，硝基，氨基，甲磺酰氧基或卤素; A 1代表低级链烷磺酰基，卤代低级链烷磺酰基，取代的苯磺酰基，低级酰基或卤代低级酰基; A 2代表氢，低级链烷磺酰基，卤代低级链烷磺酰基或低级烷基。
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2.发明授权
公开(公告)号：EP0592664B1
公开(公告)日：2000-07-05
申请号：EP91905483.3
申请日：1991-03-07
发明人： SAITA, Masaru, 855-75, Kokura , INOUE, Hisataka, 1473-10, Tsubukuhonmachi , IKESUE, Kouichi, 193-1, Yamaryo Morodomimachi , FUJIMOTO, Noriyuki, 1175-3, Sakuramachi , SHINOHARA, Ikuo, 786-1, Tashirodaikanmachi , TANIGUCHI, Yasuaki, 567-1, Tashirohokamachi , DEGUCHI, Yoshiki, 1175-3, Sakuramachi , MINAMI, Hidenao, 1032-3, Ooazafutsukaichi , NODA, Kanji, 320-93, Ooazatsunematsu
IPC分类号： C07D277/44 , C07D277/52 , C07D277/46
CPC分类号： C07D277/46 , C07D277/52
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